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Review Article

益生菌治疗炎症性肠病;深入研究它们对疾病进程和相关健康风险的影响

卷 31, 期 30, 2024

发表于: 30 April, 2024

页: [4807 - 4825] 页: 19

弟呕挨: 10.2174/0109298673314861240429072352

价格: $65

Open Access Journals Promotions 2
摘要

迄今为止，炎症性肠病(IBD)的潜在病理尚不确定。肠道菌群紊乱与包括IBD在内的许多健康疾病有关。越来越多的证据表明，益生菌在恢复肠道生态系统平衡方面发挥着有益的作用。本综述检索了多个数据库，寻找有关益生菌对成人IBD可能有益的相关研究。益生菌在溃疡性结肠炎患者和克罗恩病中的作用模式被检查了益生菌菌株，它们的益处，以及它们在成人病例中的优势。评估和分析符合纳入条件的研究。它们在缩短IBD病程、诱导和维持缓解方面有效，特别是对溃疡性结肠炎患者，具有良好的疗效和安全性。然而，克罗恩病的证据缺乏。益生菌积极影响ibd相关风险，降低胃肠道恶性肿瘤风险并优化治疗。此外，它们还提高了男女本已降低的生育几率。IBD患者的骨质疏松风险也有所降低，尽管使用时间和剂量仍未确定。在急性心肌梗死和慢性心力衰竭患者中，它们在降低IBD -心血管风险方面具有令人鼓舞的作用。最后，它们在减少ibd相关抑郁和改善整体心理健康方面有新的用途。总之，我们推荐益生菌作为IBD治疗溃疡性结肠炎的辅助治疗选择;然而，它们在克罗恩病中的作用还需要进一步研究。

关键词: 益生菌，成人，IBD相关健康风险，克罗恩病，溃疡性结肠炎，胃镜。

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