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Letters in Organic Chemistry

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ISSN (Online): 1875-6255

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Review Article

A Brief Review Depending on the Chemistry of Isatin in Single Pot Technique Towards the Construction of Significant and Valuable Heterocyclic Scaffolds

Author(s): Animesh Mondal*

Volume 21, Issue 11, 2024

Published on: 27 March, 2024

Page: [929 - 957] Pages: 29

DOI: 10.2174/0115701786292045240226050222

Price: $65

Open Access Journals Promotions 2
Abstract

The term isatin and its derivative-based MCRs have emerged over the years as a versatile, environment-friendly, and very promising platform for the construction of highly enabling bioactive organic scaffolds such as drugs, natural products, pharmaceuticals etc. In the world of recent advancements, the one-pot strategy based on isatin has come to the forefront of synthetic chemistry for the activation of small organic molecules. This present survey touched on the chemistry of isatin employed over the past decade to sketch and for the creation of various types of organic molecules consisting of heterocyclic or spiro-heterocyclic skeletons via one-pot methodology.

Keywords: Isatin, multicomponent reactions (MCRs), one-pot technique, heterocyclic scaffolds, spiro-oxindole, spiro-fused compounds.

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