Title:The Neuroprotective Properties of Thymol and Carvacrol: A Review Study
Volume: 15
Issue: 1
Author(s): Masoumeh Asle-Rousta*
Affiliation:
- Department of Physiology, Zanjan Branch, Islamic Azad University, Zanjan, Iran
Keywords:
Thymol, carvacrol, neurodegenerative diseases, oxidative stress, anti-inflammatory agents, Alzheimer's disease.
Abstract: Over the past few decades, researchers have become interested in natural compounds and
their potential to prevent and treat diseases. Phenolic monoterpenoids, thymol and carvacrol, are
quickly absorbed into the bloodstream through the gastrointestinal tract. Studies conducted in vitro
and in vivo have shown that both thymol and carvacrol have anti-inflammatory, antioxidant, and
antiapoptotic properties. Research indicates these compounds can easily cross the blood-brain barrier
and offer neuroprotective effects. They are both very safe and have no toxicity in therapeutic doses.
This review focuses on the neuroprotective effects of thymol and carvacrol and analyzes their impact
on the central nervous system, including their antioxidant and anti-inflammatory effects. The report
also highlights their potential influence on neurodegenerative diseases like Parkinson's and Alzheimer's,
emotional disorders, and brain and spinal cord ischemia.
