Title:Leptospirosis Associated Digital Gangrene of Lower Extremities: Two
Cases and Review of Literature
Volume: 24
Issue: 5
Author(s): Anju Dinkar, Jitendra Singh*Mahima Yadav
Affiliation:
- Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi,
Uttar Pradesh, India
Keywords:
Gangrene, vasculitis, weil’s disease, cellulitis, acute kidney injury, hepatitis.
Abstract:
Background: Leptospirosis is the most common zoonotic illness worldwide, caused by
pathogenic spirochete bacteria called Leptospirosis. It is clinically presented with mild to moderate in
most cases. However, sometimes, the course may be severe with multiorgan dysfunction.
Case Presentation: We present two rare cases of Leptospirosis with peripheral dry gangrene of the
lower extremities. A 25-year-old male, farmer by occupation without any significant past medical
history had been diagnosed with a case of Leptospirosis that complicated to digital gangrene on 15
days of illness during hospitalization. Another 21-year-old male student was admitted for leptospirosis
and developed digital gangrene on 19 days of illness. All clinical findings were resolved on the
steroid.
Conclusion: Apart from a high index of suspicion and awareness of unusual manifestations, serology
plays a vital role in making an accurate and quick diagnosis to initiate appropriate therapy.
