Title:Carbon Nanotubes for Targeted Therapy: Safety, Efficacy, Feasibility and
Regulatory Aspects
Volume: 30
Issue: 2
Author(s): Babita Gupta, Pramod Kumar Sharma and Rishabha Malviya*
Affiliation:
- Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India
Keywords:
Carbon nanotube, targeted delivery, drug delivery, patient care, toxicity, chemotherapeutic medications.
Abstract: It is crucial that novel and efficient drug delivery techniques be created in order to improve the pharmacological
profiles of a wide variety of classes of medicinal compounds. Carbon nanotubes (CNTs) have recently
come to the forefront as an innovative and very effective technique for transporting and translocating
medicinal compounds. CNTs were suggested and aggressively researched as multifunctional novel transporters
designed for targeted pharmaceutical distribution and used in diagnosis. CNTs can act as vectors for direct
administration of pharmaceuticals, particularly chemotherapeutic medications. Multi-walled CNTs make
up the great majority of CNT transporters, and these CNTs were used in techniques to target cancerous cells. It
is possible to employ Carbon nanotubes (CNTs) to transport bioactive peptides, proteins, nucleic acids, and
medicines by functionalizing them with these substances. Due to their low toxicity and absence of immunogenicity,
carbon nanotubes are not immunogenic. Ammonium-functionalized carbon nanotubes are also attractive
vectors for gene-encoding nucleic acids. CNTs that have been coupled with antigenic peptides have the potential
to be developed into a novel and efficient approach for the use of synthetic vaccines. CNTs bring up an
enormous number of new avenues for future medicine development depending on targets within cells, which
have until now been difficult to access. This review focuses on the numerous applications of various CNT
types used as medicine transport systems and on the utilization of CNTs for therapeutical purposes.