Title:Exploring the Potential Link between Aluminum-Containing
Deodorants/Antiperspirants and Breast Cancer: A Comprehensive
Review
Volume: 32
Issue: 3
Author(s): Tony Hangan, Geir Bjørklund*Sergiu Chirilă
Affiliation:
- Department of Research,
Council for Nutritional and Environmental Medicine, Mo i Rana, Norway
Keywords:
Aluminum, deodorants, antiperspirants, breast cancer, clinical trials, genomic instability.
Abstract: The potential association between aluminum-containing deodorants/antiperspirants
and breast cancer has been investigated and debated. This paper comprehensively
analyzes existing literature to examine the evidence and provide insights into this relationship.
This comprehensive review discusses aspects related to the absorption and distribution
of aluminum compounds, its effects on the induction of oxidative stress, the estrogenic
activity of aluminum, and potential disruption of hormonal pathways, and the
potential role in breast cancer induction. Currently, available research, consisting of epidemiological
studies as well as clinical trials, together with meta-analyses and previously
published reviews conducted on identifying the relationship between aluminum-containing
deodorants/antiperspirants and the risk of breast cancer were also analyzed and
discussed. Societal factors, personal hygiene considerations, and lifestyle changes contribute
to the increased usage of antiperspirants, but they do not establish a direct causal
connection with breast cancer. Further research employing larger-scale studies and rigorous
methodologies must validate the existing findings and explore the underlying mechanisms
involved. Continued multidisciplinary research efforts and collaboration between
researchers, regulatory bodies, and public health authorities are vital to developing a
more definitive understanding of this complex topic.
