Title:1,3,4-Thiadiazole: A Versatile Scaffold for Drug Discovery
Volume: 21
Issue: 5
Author(s): Ravi K. Mittal*, Raghav Mishra, Vikram Sharma and Isha Mishra
Affiliation:
- Galgotias College of Pharmacy, Galgotias University, Greater Noida, Uttar Pradesh, 201310, India
Keywords:
Thiadiazole, heterocycle, chemistry, properties, biological activity, structure activity relationship.
Abstract: 1,3,4-Thiadiazole has garnered considerable attention in the scientific community due to
its captivating molecular structure and ability to serve as a foundation for creating novel pharmaceutical
compounds. Numerous medications feature the 1,3,4-thiadiazole ring in their chemical structure,
highlighting its relevance and efficacy in pharmaceutical research and development. The key
objective of this comprehensive review is to provide an understandable overview of the chemistry
and diverse pharmacological activities associated with 1,3,4-thiadiazole compounds. The manuscript
was compiled by conducting a thorough literature review, which included an in-depth analysis of
globally esteemed scientific research databases. The remarkable chemical characteristics and diverse
pharmacological impacts of 1,3,4-Thiadiazole highlight its significant potential as a structural scaffold
for the development of novel therapeutic substances. Based on the information available on synthetic
molecules that incorporate the 1,3,4-thiadiazole framework and their wide range of uses, it is
reasonable to expect significant advancements in the near future and the possibility of employing
these compounds in different domains.
