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Anti-Cancer Agents in Medicinal Chemistry

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ISSN (Print): 1871-5206
ISSN (Online): 1875-5992

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Mini-Review Article

A Comprehensive Review on Nanoparticles as a Targeted Delivery System for the Treatment of Lung Cancer

Author(s): Twinkle Gupta, Avinash Varanwal, Priyanshu Nema, Sakshi Soni, Arun Kumar Iyer, Ratnesh Das, Vandana Soni and Sushil Kumar Kashaw*

Volume 24, Issue 3, 2024

Published on: 27 November, 2023

Page: [157 - 168] Pages: 12

DOI: 10.2174/0118715206257442231109202235

Price: $65

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Abstract

The second most common type of cancer is lung cancer, impacting the human population. Lung cancer is treated with a number of surgical and non-surgical therapies, including radiation, chemotherapy, and photodynamic treatment. However, the bulk of these procedures are costly, difficult, and hostile to patients. Chemotherapy is distinguished by inadequate tumour targeting, low drug solubility, and insufficient drug transport to the tumour site. In order to deal with the issues related to chemotherapy, extensive efforts are underway to develop and investigate various types of nanoparticles, both organic and inorganic, for the treatment of lung cancer. The subject of this review is the advancements in research pertaining to active targeted lung cancer nano-drug delivery systems treatment, with a specific emphasis on receptors or targets. The findings of this study are expected to assist biomedical researchers in utilizing nanoparticles (NPs) as innovative tools for lung cancer treatment, offering new methods for delivering drugs and reliable solid ligands.

Keywords: Nanoparticles, lung cancer, targeted delivery, nanocarriers, polymeric nanoparticles, chemotherapy.

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Graphical Abstract

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