Title:A Critical Study on the Synthetic and Herbal Medication Pattern in the
Management of Psoriasis
Volume: 10
Author(s): Shobhini Chandel*, Saumya Das, Neha Neha and Vijayant Singh Chauhan
Affiliation:
- Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park-2, Greater Noida, G.B Nagar,
Uttar Pradesh 201306, India
Keywords:
Psoriasis, Cytokines, Methotrexate, Biologicals, Phototherapeutics, Herbal treatments, Capsicum frutescens
Abstract: Psoriasis is a persistent skin illness that causes dense, shimmering flakes, irritable,
dry, and red patches as a result of the fast buildup of skin cells. It is an autoimmune skin condition
that is incurable, non-contagious, and relapsing-remitting. Typically, a remission phase lasts
one to twelve months. Psoriasis is caused by a number of cellular mechanisms, and it has been
hypothesised that T lymphocytes, keratinocytes, allergen cells, Langerhans cells, natural killer
cells, phagocytes, a number of Th1-type chemokines, in addition to growth factors like
endothelial proliferation factor and keratinocytes growth factor, among others, are key players in
the development of psoriasis. Numerous synthetic medicinal drugs have been documented to
have the side effects of psoriasis. Due to the safety and accessibility, herbal medications may
hold promise as possible anti-psoriatic molecules. Before creating a potential herbal drug, it is
important to thoroughly examine the key players in the evolution of psoriasis, such as T-cell
stimulation, transportation, and cytokinase inhibition. The purpose of this review is to investigate
how psoriasis spreads and becomes activated, as well as how certain medications might
exacerbate the condition and how certain plant resources may be used to treat psoriasis. To
create a potent, secure, and dependable treatment, more scientific research on these herbal
resources is required.
