Medicinal Attributes of Pyrazoline in Drug Discovery

Title:Medicinal Attributes of Pyrazoline in Drug Discovery

Volume: 21 Issue: 14

Author(s): Disha Arora, Jyoti Singh*Sandeep Kumar

Affiliation:

• Chandigarh College of Pharmacy, Landran, Punjab, India

Keywords: Pyrazoline, anticonvulsant, antimalarial, antimicrobial, antifungal, antidepressant, anti-inflammatory, antinociceptive, antitubercular, antiameobic, anti-schistosomal, insecticidal, hypotensive, antiviral, antioxidant and anticancer : Pyrazoline, antioxidant and anticancer

Abstract: Pyrazoline are structurally versatile nitrogen-containing heterocycle that has gained more attention owing to its diversified pharmacological activities. This special scaffold serves as a fundamental component in a variety of bioactive chemicals, enabling the creation of new molecules with advantageous biological functions. The present review paper provides a summary of diversified pharmacological activities in particular, anticancer, antimalarial, antimicrobial, antifungal, antidepressant, anti-inflammatory, antinociceptive, antitubercular, anticonvulsant, anti-amoebic, antischistosomal, insecticidal, hypotensive, antiviral, antioxidant and anti-trypanosomal activity. This review also presents numerous simple synthetic techniques for the preparation of pyrazolines and also highlights the applicability of pyrazoline in drug discovery.

Cite this article as:

Arora Disha, Singh Jyoti*, Kumar Sandeep, Medicinal Attributes of Pyrazoline in Drug Discovery, Letters in Drug Design & Discovery 2024; 21 (14) . https://dx.doi.org/10.2174/0115701808268325231008093015