Title:Nanomedicine: Innovative Strategies and Recent Advances in
Targeted Cancer Therapy
Volume: 31
Issue: 28
Author(s): Rupesh K. Gautam*, Pooja Mittal, Rajat Goyal, Kamal Dua, Dinesh Kumar Mishra, Sanjay Sharma and Rajeev Kumar Singla*
Affiliation:
- Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care
Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China
- Department of Pharmaceutics, Indore Institute of Pharmacy, IIST Campus, Rau, Indore, 453331, Madhya Pradesh, India
- Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care
Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China
- School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, 144411, India
Keywords:
Nanomedicine, nanotechnology, cancer, apoptosis, cell proliferation, drug delivery, nanoparticles.
Abstract: Nanomedicine's application of nanotechnology in medicine holds tremendous potential
for diagnosing and treating life-threatening diseases such as cancer. Unlike conventional therapies,
nanomedicine offers a promising strategy to enhance clinical outcomes while minimizing severe
side effects. The principle of drug targeting enables specific delivery of therapeutic agents to
their intended sites, making it a more precise and effective therapy. Combination strategies, such
as the co-delivery of chemotherapeutic drugs with nucleic acids or receptor-specific molecules,
are being employed to enhance therapeutic outcomes. Nanocarriers and drug delivery systems designed
using these approaches offer resourceful co-delivery of therapeutic agents for anticancer
therapy. Targeted drug delivery via nanotechnology-based techniques has become an urgent need
and has shown significant improvements in therapeutic implications, pharmacokinetics, specificity,
reduced toxicity, and biocompatibility. This review discusses the extrapolation of nanomaterials
for developing innovative and novel drug delivery systems for effective anticancer therapy.
Additionally, we explore the role of nanotechnology-based concepts in drug delivery research.
