Title:The Antiviral Potential of Zingiber officinale (Ginger): A Comprehensive Literature Review
Volume: 10
Author(s): Mohammad Amin Amini fard, Mahsa Asadi Anar, Gisou Erabi*, Farhad Nikzad, Mehran Ghasemi, Mahdi Seyfi-Ghale-Jogh, Fateme Javaherchian, Ladan baghban, Amir Jafari, Sepehr Olangian-Tehrani, Sepehr Nanbakhsh, Niloofar Deravi, Zohreh Tutunchian, Tina Mansourian, Fariba Arbab Mojeni, Alaleh Alizadeh, Farzad Sheikhzadeh, Parisa alsadat Dadkhah and Fatemeh Chichagi
Affiliation:
- Urmia University of Medical Sciences Student research committee Urmia Iran
Keywords:
Ginger, Zingiber Officinale, Antiviral, COVID-19, SARS-CoV-2, zingerone
Abstract: Herbal medicine has gained massive popularity among researchers worldwide. The
leading causes of this rapid development are lower side effects, lower prices, and higher availability
of plant extracts compared to synthetic drugs. Ginger (Zingiber officinale), from the Zingiberaceae
family, is one of the most commonly used and popular plants utilized as a dietary spice,
herbal medicine, and food preservative. Its biologically active components, such as shogaol, paradol,
zingerone, and especially gingerol, can be highly effective for the treatment of several illnesses
through various anti-inflammatory, anti-neoplastic, anti-emetic, anti-oxidant, antihyperlipidemic
and anti-hyperglycaemic activities. Ginger can also be used as an antiviral agent.
Numerous studies have been conducted to investigate the antiviral efficacy of ginger on several
viruses; for instance, severe acute respiratory syndrome 2 (SARS-COV-2), influenza, dengue,
hepatitis, herpes, Human Papilloma Virus (HPV), Human Immunodeficiency Virus (HIV), Epstein-
Barr Virus (EBV), Chikungunya virus and so on. This review summarizes the efficacy of
ginger in preventing or treating several viral diseases and its mechanism of action, emphasizing
coronavirus disease 2019 (COVID-19) due to the current high burden of disease worldwide.
