Title:In-depth Chemistry and Pharmacological Potential of Propolis: A Critical
Review of Recent Developments
Volume: 10
Issue: 7
Author(s): Jyotsana Dwivedi*, Pranjal Sachan, Pranay Wal and A. K. Rai
Affiliation:
- PSIT-Pranveer Singh Institute of Technology (Pharmacy), Kanpur, 209305, India
Keywords:
Propolis, chemical constituents, pharmacological activity, traditional uses.
Abstract:
Background: One of the most popular beekeeping products is propolis. The word "propolis,"
which alludes to a beehive, has Greek sources and implies "defense for the community."
Propolis is a resinous material that honey worker bees (Apis mellifera L.) and other bee species
make for a variety of uses. Since 300 BC, propolis has been used as a traditional remedy. Various
pharmacological effects of distinct propolis extracts as well as those of its ingredients, including antioxidant,
antiulcer, anticancer, antiviral, anti-microbial, anti-inflammatory, and antifungal characteristics,
have recently been identified.
Objective: In this review article, we focus on the origin, recent advances in the chemical constituents,
and new therapeutic potential of propolis.
Materials and Methods: An exhaustive analysis of the literature search was conducted. The standard
keywords "propolis," "origin," "chemical constituents," "pharmacological activity," "recent advances,"
and "traditional uses" have been used to search a variety of the standard databases, such as
Scopus and Elsevier, PubMed, ScienceDirect, and Science Web, for research and review articles
published between 1998 and 2023.
Results: This review article included over 150 articles (research and reviews) that were appraised
and researched.
Conclusion: Since 2012, more than 300 substances have been shown to have pharmacological action
against a variety of illnesses, including cancer, inflammation, ulcers, wound healing, diabetes,
bacterial, viral, and fungal infections, hepatic disorders, dental problems, brain diseases, etc. Overall,
propolis may be considered a source of bioactive compounds for pharmaceutical development.
Future studies should consider plant types, regional conditions, bee subspecies, and variations.