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The Natural Products Journal

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ISSN (Print): 2210-3155
ISSN (Online): 2210-3163

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Mini-Review Article

A Comprehensive Study on Natural Products and their Bioactive Constituents to Cure Respiratory Diseases

Author(s): Avadh Biharee, Lokesh Chaudhari, Sudha Bhartiya, Shivam Kumar Kori, Anu Chaudhary, Dheeraj Dubey and Arpita Yadav*

Volume 14, Issue 2, 2024

Published on: 31 July, 2023

Article ID: e120623217879 Pages: 39

DOI: 10.2174/2210315513666230612111133

Price: $65

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Abstract

Background: In terms of death rates, occurrence, costs, and prevalence, respiratory tract diseases, which include minor issues like the common cold and life-threatening ones like bacterial pneumonia, lung cancers, and tuberculosis, are extremely significant. People have been worried about their health for a long time because of respiratory diseases. Old-style medication has tended to these diseases; however, the accumulation of information produced by elective methodologies, among which medication assumes a significant role, is insignificant. Phytotherapy has consistently given proficient solutions for constant and moderate wellbeing inconveniences and, occasionally, for intense and serious problems. Alleviating the aggravated nasal sections and aviation routes was a shared need in antiquated societies. In this study, we conducted a systematic literature review to gain evidence about herbal products and their phytoconstituents that play a role in respiratory illness. We also predicted the physicochemical properties of various phytoconstituents from therapeutic plants employed to cure respiratory ailments (such as asthma, COPD, cough, tuberculosis, etc.).

Objectives: The main objective of this critical study is to explore phytotherapy-based molecules for respiratory illnesses. The physicochemical properties of already isolated compounds have been evaluated to screen for the drug-like behavior of phytoconstituents.

Methodology: A wide variety of literature has been collected from PubMed, Google Scholar, Medline, and other scientific databases. After an exhaustive review, the chemical structures of phytoconstituents responsible for curing respiratory illness were sketched in ChemDraw Ultra 8.0, and these structures have been taken for further analysis of the physicochemical properties of these phytoconstituents. The crucial parameters of phytoconstituents' physicochemical properties were analyzed using the pkCSM webserver.

Result: The results suggest that a variety of phytoconstituents have the potential to treat respiratory illnesses, and the physicochemical parameters reveal that 65 compounds out of 130 screened compounds exhibit Lipinski's rule of five and Veber's rule, while others don't obey these rules. Compounds with optimal physicochemical properties could be promising candidates for emerging respiratory illness treatments.

Conclusion: This critical review highlights the possible therapeutic potential of plant-based medicine to cure respiratory illnesses. The finding shows that a wide range of alkaloids, glycosides, terpenoids, and flavonoids isolated from different herbs may be able to treat respiratory problems. More research is needed to find out the IC50 and MIC values of these compounds against respiratory pathogens like S. pneumoniae and M. tuberculosis.

Keywords: Respiratory illness, asthma, COPD, physicochemical properties, lipinski's rule, veber's rule.

Graphical Abstract

[1]
Ciprandi, G.; Caimmi, D.; Miraglia del Giudice, M.; La Rosa, M.; Salpietro, C.; Marseglia, G.L. Recent developments in united airways disease. Allergy Asthma Immunol. Res., 2012, 4(4), 171-177.
[http://dx.doi.org/10.4168/aair.2012.4.4.171] [PMID: 22754709]
[2]
Tan, W.C.; Bourbeau, J.; Hernandez, P.; Chapman, K.R.; Cowie, R.; FitzGerald, J.M.; Marciniuk, D.D.; Maltais, F.; Buist, A.S.; O’Donnell, D.E.; Sin, D.D.; Aaron, S.D. Exacerbation-like respiratory symptoms in individuals without chronic obstructive pulmonary disease: Results from a population-based study. Thorax, 2014, 69(8), 709-717.
[http://dx.doi.org/10.1136/thoraxjnl-2013-205048] [PMID: 24706040]
[3]
Rigat, M.; Vallès, J.; Iglésias, J.; Garnatje, T. Traditional and alternative natural therapeutic products used in the treatment of respiratory tract infectious diseases in the eastern Catalan Pyrenees (Iberian Peninsula). J. Ethnopharmacol., 2013, 148(2), 411-422.
[http://dx.doi.org/10.1016/j.jep.2013.04.022] [PMID: 23612419]
[4]
De Blasio, F.; Virchow, J.C.; Polverino, M.; Zanasi, A.; Behrakis, P.K.; Kilinç, G.; Balsamo, R.; De Danieli, G.; Lanata, L. Cough management: A practical approach. Cough, 2011, 7(1), 7.
[http://dx.doi.org/10.1186/1745-9974-7-7] [PMID: 21985340]
[5]
Cotes, J.E.; Chinn, D.J.; Miller, M.R. Lung function: Physiology, measurement and application in medicine; John Wiley & Sons, 2009.
[6]
Gutiérrez, R.M.P.; Perez, R.L. Raphanus sativus (Radish): Their chemistry and biology. Sci. World J., 2004, 4, 811-837.
[http://dx.doi.org/10.1100/tsw.2004.131] [PMID: 15452648]
[7]
Johannson, K.A.; Balmes, J.R.; Collard, H.R. Air pollution exposure: A novel environmental risk factor for interstitial lung disease? Chest, 2015, 147(4), 1161-1167.
[http://dx.doi.org/10.1378/chest.14-1299] [PMID: 25846532]
[8]
Hwang, Y.Y.; Ho, Y.S. Nutraceutical support for respiratory diseases. Food Sci. Hum. Wellness, 2018, 7(3), 205-208.
[http://dx.doi.org/10.1016/j.fshw.2018.09.001]
[9]
MacPherson, P.; Steingart, K.; Garner, P.; Medley, N. WHO consolidated guidelines on tuberculosis module 2: Screening–systematic screening for tuberculosis disease; World Health Organization, 2021.
[10]
MacNeil, A.; Glaziou, P.; Sismanidis, C.; Date, A.; Maloney, S.; Floyd, K. Global epidemiology of tuberculosis and progress toward meeting global targets-worldwide, 2018. MMWR Morb. Mortal. Wkly. Rep., 2020, 69(11), 281-285.
[http://dx.doi.org/10.15585/mmwr.mm6911a2] [PMID: 32191687]
[11]
Halpin, D.M.G.; Celli, B.R.; Criner, G.J.; Frith, P.; López Varela, M.V.; Salvi, S.; Vogelmeier, C.F.; Chen, R.; Mortimer, K.; Montes de Oca, M.; Aisanov, Z.; Obaseki, D.; Decker, R.; Agusti, A. The gold summit on chronic obstructive pulmonary disease in low- and middle-income countries. Int. J. Tuberc. Lung Dis., 2019, 23(11), 1131-1141.
[http://dx.doi.org/10.5588/ijtld.19.0397] [PMID: 31718748]
[12]
Boehm, A.; Pizzini, A.; Sonnweber, T.; Loeffler-Ragg, J.; Lamina, C.; Weiss, G.; Tancevski, I. Assessing global COPD awareness with Google Trends. Eur. Respir. J., 2019, 53(6), 1900351.
[http://dx.doi.org/10.1183/13993003.00351-2019] [PMID: 31097517]
[13]
Cragg, G.M.; Boyd, M.R.; Khanna, R.; Newman, D.J.; Sausville, E.A. Natural product drug discovery and development. In: Phytochemicals in Human Health Protection, Nutrition, and Plant Defense; Springer, 1999, pp. 1-29.
[14]
Nasir, B.; Fatima, H.; Ahmed, M.; Haq, I. Recent trends and methods in antimicrobial drug discovery from plant sources. Austin J Microbiol., 2015, 1(1), 1-12.
[15]
Newman, D.J.; Cragg, G.M. Natural products as sources of new drugs from 1981 to 2014. J. Nat. Prod., 2016, 79(3), 629-661.
[http://dx.doi.org/10.1021/acs.jnatprod.5b01055] [PMID: 26852623]
[16]
Md., Mahadi; Hasan, A.S.H.; Magdy, A. Al-kordy; Ahmed, Ramadan Present status of valuable medicinal plant Withania somnifera (L.) Dunal in Saudi Arabia - A review. Int. J. Curr. Life Sci., 2015, 5(3), 510-515.
[17]
Ekor, M. The growing use of herbal medicines: Issues relating to adverse reactions and challenges in monitoring safety. Front. Pharmacol., 2014, 4, 177.
[http://dx.doi.org/10.3389/fphar.2013.00177] [PMID: 24454289]
[18]
Lai, P.; Roy, J. Antimicrobial and chemopreventive properties of herbs and spices. Curr. Med. Chem., 2004, 11(11), 1451-1460.
[http://dx.doi.org/10.2174/0929867043365107] [PMID: 15180577]
[19]
Jahan, Y.; Mahmood, T.; Bagga, P. Future prospects of cough treatment, herbal medicines v/s modern drugs. Int. J. Pharm. Sci. Res., 2015, 6(9), 1000-1009.
[20]
Gairola, S.; Gupta, V.; Bansal, P.; Singh, R.; Maithani, M. Herbal antitussives and expectorants - a review. Int. J. Pharm. Sci. Rev. Res., 2010, 5(2), 5-9.
[21]
Mehvish, S.; Barkat, M.Q. Phytochemical and antioxidant screening of Amomum subulatum, Elettaria cardamomum, Emblica officinalis, Rosa damascene, Santalum album and Valeriana officinalis and their effect on stomach, liver and heart. Matrix Science Medica, 2018, 2(2), 28-33.
[http://dx.doi.org/10.26480/msm.02.2018.28.33]
[22]
Lim, T. Ginkgo biloba. Edible Medicinal And Non Medicinal Plants; Springer, 2012, pp. 1-44.
[23]
Paul, S.; Chakraborty, S.; Anand, U.; Dey, S.; Nandy, S.; Ghorai, M.; Saha, S.C.; Patil, M.T.; Kandimalla, R. Pročków, J.; Dey, A. Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological aspects. Biomed. Pharmacother., 2021, 143, 112175.
[http://dx.doi.org/10.1016/j.biopha.2021.112175] [PMID: 34649336]
[24]
Wagner, C.S.; De Gezelle, J.; Robertson, M.; Robertson, K.; Wilson, M.; Komarnytsky, S. Antibacterial activity of medicinal plants from The Physicians of Myddvai, a 14th century Welsh medical manuscript. J. Ethnopharmacol., 2017, 203, 171-181.
[http://dx.doi.org/10.1016/j.jep.2017.03.039] [PMID: 28344030]
[25]
Thakur, A.K.; Raj, P. Pharmacological perspective of Glycyrrhiza glabra Linn: A mini-review. J. Anal. Pharm. Res., 2017, 5(5), 00156.
[http://dx.doi.org/10.15406/japlr.2017.05.00156]
[26]
Imtiyaz, S.; Rahman, K.; Sultana, A.; Tariq, M. Chaudhary, SS Zingiber officinale Rosc.: A traditional herb with medicinal properties. Cell Med., 2013, 3(4), 26-27.
[27]
Suliman, S.; Van Vuuren, S.F.; Viljoen, A.M. Validating the in vitro antimicrobial activity of Artemisia afra in polyherbal combinations to treat respiratory infections. S. Afr. J. Bot., 2010, 76(4), 655-661.
[http://dx.doi.org/10.1016/j.sajb.2010.07.003]
[28]
Madikizela, B.; Ndhlala, A.R.; Finnie, J.F.; Van Staden, J. Antimycobacterial, anti-inflammatory and genotoxicity evaluation of plants used for the treatment of tuberculosis and related symptoms in South Africa. J. Ethnopharmacol., 2014, 153(2), 386-391.
[http://dx.doi.org/10.1016/j.jep.2014.02.034] [PMID: 24576406]
[29]
Rajaram, A.; Vanaja, G.R.; Vyakaranam, P.; Rachamallu, A.; Reddy, G.V.; Anilkumar, K.; Arunasree, K.M.; Dhyani, A.; Prasad, N.K.; Sharma, S.; Chandra Joshi, M.; Kimothi, G.P.; Brindavanam, N.B.; Reddanna, P. Anti-inflammatory profile of Aegle marmelos (L) Correa (Bilva) with special reference to young roots grown in different parts of India. J. Ayurveda Integr. Med., 2018, 9(2), 90-98.
[http://dx.doi.org/10.1016/j.jaim.2017.03.006] [PMID: 29239790]
[30]
Dwita, L.P.; Hikmawanti, N.P.E. Yeni; Supandi, Extract, fractions, and ethyl-p-methoxycinnamate isolate from Kaempferia galanga Elicit anti-inflammatory activity by limiting leukotriene B4 (LTB4) production. J. Tradit. Complement. Med., 2021, 11(6), 563-569.
[http://dx.doi.org/10.1016/j.jtcme.2021.06.004] [PMID: 34765520]
[31]
Saluja, P.; Shukla, K.; Yadav, H. Antiarthritic activity of ethano-medicinal herbal plants. IOSR J. Environ. Sci. Toxicol. Food Technol., 2015, 1(5), 12-23.
[32]
Cotabarren, J.; Lufrano, D.; Parisi, M.G.; Obregón, W.D. Biotechnological, biomedical, and agronomical applications of plant protease inhibitors with high stability: A systematic review. Plant Sci., 2020, 292, 110398.
[http://dx.doi.org/10.1016/j.plantsci.2019.110398] [PMID: 32005400]
[33]
Rodino, S.; Butu, M. 3 - Herbal Extracts—New Trends in Functional and Medicinal Beverages. In: Functional and Medicinal Beverages; Elsevier, 2019, 11, pp. 73-108.
[34]
Gautam, R.; Saklani, A.; Jachak, S.M. Indian medicinal plants as a source of antimycobacterial agents. J. Ethnopharmacol., 2007, 110(2), 200-234.
[http://dx.doi.org/10.1016/j.jep.2006.12.031] [PMID: 17276637]
[35]
Kuang, Y.; Li, B.; Fan, J.; Qiao, X.; Ye, M. Antitussive and expectorant activities of licorice and its major compounds. Bioorg. Med. Chem., 2018, 26(1), 278-284.
[http://dx.doi.org/10.1016/j.bmc.2017.11.046] [PMID: 29224994]
[36]
Saludes, J.P.; Garson, M.J.; Franzblau, S.G.; Aguinaldo, A.M. Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae). Phytother. Res., 2002, 16(7), 683-685.
[http://dx.doi.org/10.1002/ptr.1003] [PMID: 12410555]
[37]
Amir, F.; Chin, K.Y. The chemical constituents and pharmacology of Centratherum anthelminticum. Int. J. Pharm. Tech. Res., 2011, 3, 1772-1779.
[38]
Parui, S.; Mandal, S. Biochemical analysis and skin sensitivity test of the allergenic pollen of Datura metel L. Curr. Sci., 1998, 74(1), 66-68.
[39]
Ahmad, S.S. Medicinal wild plants from Lahore-Islamabad motorway (M-2). Pak. J. Bot., 2007, 39(2), 355.
[40]
Ghazi-Moghadam, K. Inançlı H.M.; Bazazy, N.; Plinkert, P.K.; Efferth, T.; Sertel, S. Phytomedicine in otorhinolaryngology and pulmonology: Clinical trials with herbal remedies. Pharmaceuticals, 2012, 5(8), 853-874.
[http://dx.doi.org/10.3390/ph5080853] [PMID: 24280678]
[41]
Khan, Z.H.; Faruquee, H.M.; Shaik, M.M. Phytochemistry and pharmacological potential of Terminalia arjuna L. Med Plant Res., 2013, 3(10), 70-77.
[42]
Ramgopal, K.; Kumar, C.R. Critical review of herbs acting on pranavaha srotovikar. Int. J. Ayurveda Pharma Res., 2013, 1(3), 19-26.
[43]
Saikia, D.; Parveen, S.; Gupta, V.K.; Luqman, S. Anti-tuberculosis activity of Indian grass KHUS (Vetiveria zizanioides L. Nash). Complement. Ther. Med., 2012, 20(6), 434-436.
[http://dx.doi.org/10.1016/j.ctim.2012.07.010] [PMID: 23131375]
[44]
Nguyen, M.N.T.; Ho-Huynh, T.D. Selective cytotoxicity of a Vietnamese traditional formula, Nam Dia long, against MCF-7 cells by synergistic effects. BMC Complement. Altern. Med., 2016, 16(1), 220.
[http://dx.doi.org/10.1186/s12906-016-1212-z] [PMID: 27421261]
[45]
Khan, S.W.; Khatoon, S. Ethnobotanical studies on some useful herbs of Haramosh and Bugrote valleys in Gilgit, northern areas of Pakistan. Pak. J. Bot., 2008, 40(1), 43.
[46]
Shah, M Hussain, F onservation assessment of plant resources of Chakesar valley, district Shangla, KPK, Pakistan. Pak. J. Bot., 2012, 44((SI)), 179-186.
[47]
Hamayun, M.; Khan, S.A.; Sohn, E.Y.; Lee, I-J. Folk medicinal knowledge and conservation status of some economically valued medicinal plants of District Swat, Pakistan. Lyonia., 2006, 11(2), 101-113.
[48]
Ninave, P.B.; Patil, S.D. Antiasthmatic potential of Zizyphus jujuba Mill and Jujuboside B. – Possible role in the treatment of asthma. Respir. Physiol. Neurobiol., 2019, 260, 28-36.
[http://dx.doi.org/10.1016/j.resp.2018.12.001] [PMID: 30521862]
[49]
Khan, M.A. Chemical composition and medicinal properties of Nigella sativa Linn. Inflammopharmacology, 1999, 7(1), 15-35.
[http://dx.doi.org/10.1007/s10787-999-0023-y] [PMID: 17657444]
[50]
Patel, P.K.; Patel, K.V.; Gandhi, T.R. Evaluation of effect of Taxus baccata leaves extract on bronchoconstriction and bronchial hyperreactivity in experimental animals. J. Young Pharm., 2011, 3(1), 41-47.
[http://dx.doi.org/10.4103/0975-1483.76418] [PMID: 21607053]
[51]
Lee, S.H.; Sohn, Y.S.; Kang, K.K.; Kwon, J.W.; Yoo, M. Inhibitory effect of DA-9201, an extract of Oryza sativa L., on airway inflammation and bronchial hyperresponsiveness in mouse asthma model. Biol. Pharm. Bull., 2006, 29(6), 1148-1153.
[http://dx.doi.org/10.1248/bpb.29.1148] [PMID: 16755008]
[52]
Hamill, F.A.; Apio, S.; Mubiru, N.K.; Bukenya-Ziraba, R.; Mosango, M.; Maganyi, O.W.; Soejarto, D.D. Traditional herbal drugs of Southern Uganda, II: literature analysis and antimicrobial assays. J. Ethnopharmacol., 2003, 84(1), 57-78.
[http://dx.doi.org/10.1016/S0378-8741(02)00289-1] [PMID: 12499078]
[53]
Rehman, K.; Mashwani, Z.R.; Khan, M.A.; Ullah, Z.; Chaudhary, H.J. An ethno botanical perspective of traditional medicinal plants from the Khattak tribe of Chonthra Karak, Pakistan. J. Ethnopharmacol., 2015, 165, 251-259.
[http://dx.doi.org/10.1016/j.jep.2015.02.035] [PMID: 25732837]
[54]
Qureshi, R.; Ahmad, M. Some notes on the vegetation of Achhro thar (white desert) of Nara region, Sindh, Pakistan. Pak. J. Bot., 2010, 42(5), 2985-2994.
[55]
Nisar, M.F.; Jaleel, F.; Waseem, M.; Ismail, S.; Toor, Y.; Haider, S.M.; Zhong, J.L. Ethno-medicinal uses of plants from district Bahawalpur, Pakistan. Curr. Res. J. Biol. Sci., 2014, 6(5), 183-190.
[http://dx.doi.org/10.19026/crjbs.6.5191]
[56]
Ikram, S.; Bhatti, K.H.; Parvaiz, M. Ethnobotanical studies of aquatic plants of district Sialkot, Punjab (Pakistan). Faslnamah-i Giyahan-i Daruyi, 2014, 2(1), 58-63.
[57]
Hussain, I.; Bano, A.; Ullah, F. Traditional drug therapies from various medicinal plants of central karakoram national park, Gilgit-Baltistan Pakistan. Pak. J. Bot., 2011, 43, 79-84.
[58]
Ishtiaq, M.; Mahmood, A.; Maqbool, M. Indigenous knowledge of medicinal plants from Sudhanoti district (AJK), Pakistan. J. Ethnopharmacol., 2015, 168, 201-207.
[http://dx.doi.org/10.1016/j.jep.2015.01.054] [PMID: 25666425]
[59]
Mahmood, A.; Mahmood, A.; Malik, R.N. Indigenous knowledge of medicinal plants from Leepa valley, Azad Jammu and Kashmir, Pakistan. J. Ethnopharmacol., 2012, 143(1), 338-346.
[http://dx.doi.org/10.1016/j.jep.2012.06.046] [PMID: 22789966]
[60]
Khan, I.; Razzaq, I.M. Ethnobotanical studies of some medicinal and aromatic plants of higher altitude of Pakistan. Ameri-Eur J Agric Env Sci., 2007, 2, 470-473.
[61]
Shaheen, H.; Qureshi, R.; Akram, A.; Gulfraz, M. Inventory of medicinal flora from Thal Desert, Punjab, Pakistan. Afr. J. Tradit. Complement. Altern. Med., 2014, 11(3), 282-290.
[http://dx.doi.org/10.4314/ajtcam.v11i3.39] [PMID: 25371594]
[62]
Abbas, Q.; Khan, S.W.; Khatoon, S. Floristic biodiversity and traditional uses of medicinal plants of Haramosh valley Central Karakoram National Park of Gilgit district, Gilgit-Baltistan. J. Biol. Environ. Sci., 2014, 5, 75-86.
[63]
Boskabady, M.; Rakhshandah, H.; Moetamed Shariati, V. Bronchodilatory and an ticholinergic effects of Carum copticum on isolated Guinea Pig tracheal chains. Med. J. Islam. Repub. Iran, 1998, 11(4), 329-334.
[64]
Khan, K.; Alamgeer, E.A.; Ahmad, B. Ethnobotanical studies from northern areas of Pakistan. Pharmacologyonline, 2009, 1, 328-354.
[65]
Fomogne-Fodjo, M.C.Y.; Van Vuuren, S.; Ndinteh, D.T.; Krause, R.W.M.; Olivier, D.K. Antibacterial activities of plants from Central Africa used traditionally by the Bakola pygmies for treating respiratory and tuberculosis-related symptoms. J. Ethnopharmacol., 2014, 155(1), 123-131.
[http://dx.doi.org/10.1016/j.jep.2014.04.032] [PMID: 24786571]
[66]
Hutchings, A. Zulu medicinal plants: An inventory; University of Natal press, 1996.
[67]
Green, E.; Samie, A.; Obi, C.L.; Bessong, P.O.; Ndip, R.N. Inhibitory properties of selected South African medicinal plants against Mycobacterium tuberculosis. J. Ethnopharmacol., 2010, 130(1), 151-157.
[http://dx.doi.org/10.1016/j.jep.2010.04.033] [PMID: 20447452]
[68]
Betti, J.L. An ethnobotanical study of medicinal plants among the Baka pygmies in the Dja biosphere reserve, Cameroon. Afr. Study Monogr., 2004, 25(1), 1-27.
[69]
Anywar, G.; Kakudidi, E.; Byamukama, R.; Mukonzo, J.; Schubert, A.; Oryem-Origa, H. Indigenous traditional knowledge of medicinal plants used by herbalists in treating opportunistic infections among people living with HIV/AIDS in Uganda. J. Ethnopharmacol., 2020, 246, 112205.
[http://dx.doi.org/10.1016/j.jep.2019.112205] [PMID: 31476442]
[70]
Maroyi, A. An ethnobotanical survey of medicinal plants used by the people in Nhema communal area, Zimbabwe. J. Ethnopharmacol., 2011, 136(2), 347-354.
[http://dx.doi.org/10.1016/j.jep.2011.05.003] [PMID: 21575701]
[71]
Gbekley, H.E.; Katawa, G.; Karou, S.D.; Anani, K.; Tchadjobo, T.; Ameyapoh, Y.; Batawila, K.; Simpore, J. Ethnobotanical study of plants used to treat asthma in the maritime region in Togo. Afr. J. Tradit. Complement. Altern. Med., 2016, 14(1), 196-212.
[http://dx.doi.org/10.21010/ajtcam.v14i1.22] [PMID: 28480398]
[72]
Erasto, P.; Adebola, P.; Grierson, D.; Afolayan, A. An ethnobotanical study of plants used for the treatment of diabetes in the Eastern Cape Province, South Africa. Afr. J. Biotechnol., 2005, 4(12)
[73]
Van Wyk, B-E.; Gericke, N. People’s plants: A guide to useful plants of Southern Africa; Briza publications, 2000.
[74]
Nadkarni, KM Indian materia medica]; Dr. KM Nadkarni's Indian materia medica: with Ayurvedic, Unani-Tibbi, Siddha, allopathic, homeopathic, naturopathic & home remedies, appendices & indexes. 1: Popular Prakashan;; Popular Prakashan Private Ltd, 1996.
[75]
Yousaf, M.Z. Ethnobotanical studies of Khushab District, Punjab, Pakistan. Eur. J. Appl. Sci. Tech., 2014, 1(4)
[76]
Kayode, J. Conservation of indigenous medicinal botanicals in Ekiti State, Nigeria. J. Zhejiang Univ. Sci. B, 2006, 7(9), 713-718.
[http://dx.doi.org/10.1631/jzus.2006.B0713] [PMID: 16909472]
[77]
Sonibare, M.A.; Gbile, Z.O. Ethnobotanical survey of anti-asthmatic plants in South Western Nigeria. Afr. J. Tradit. Complement. Altern. Med., 2008, 5(4), 340-345.
[http://dx.doi.org/10.4314/ajtcam.v5i4.31288] [PMID: 20161955]
[78]
Mann, A.; Amupitan, J.; Oyewale, A.; Okogun, J.; Ibrahim, K. An Ethnobotanical survey of indigenous flora for treating tuberculosis and other respiratory diseases in Niger State, Nigeria. J Phytomedicine Ther., 2007, 12, 1-21.
[79]
Ibekwe, N.N.; Nvau, J.B.; Oladosu, P.O.; Usman, A.M.; Ibrahim, K.; Boshoff, H.I.; Dowd, C.S.; Orisadipe, A.T.; Aiyelaagbe, O.; Adesomoju, A.A.; Barry, C.E., III; Okogun, J.I. Some Nigerian anti-tuberculosis ethnomedicines: A preliminary efficacy assessment. J. Ethnopharmacol., 2014, 155(1), 524-532.
[http://dx.doi.org/10.1016/j.jep.2014.05.059] [PMID: 24911338]
[80]
Hamayun, M. Ethnobotanical studies of some useful shrubs and trees of District Buner, NWFP, Pakistan. Ethnobot leafl, 2003, 1, 12.
[81]
Disengomoka, I.; Delaveau, P. Medicinal plants used for child’s respiratory diseases in Zaire. Part I. J. Ethnopharmacol., 1983, 8(3), 257-263.
[http://dx.doi.org/10.1016/0378-8741(83)90063-6] [PMID: 6645575]
[82]
Bunalema, L.; Obakiro, S.; Tabuti, J.R.S.; Waako, P. Knowledge on plants used traditionally in the treatment of tuberculosis in Uganda. J. Ethnopharmacol., 2014, 151(2), 999-1004.
[http://dx.doi.org/10.1016/j.jep.2013.12.020] [PMID: 24365640]
[83]
Mugisha, M.K.; Asiimwe, S.; Namutebi, A.; Borg-Karlson, A.K.; Kakudidi, E.K. Ethnobotanical study of indigenous knowledge on medicinal and nutritious plants used to manage opportunistic infections associated with HIV/AIDS in western Uganda. J. Ethnopharmacol., 2014, 155(1), 194-202.
[http://dx.doi.org/10.1016/j.jep.2014.05.012] [PMID: 24862490]
[84]
Alamgeer; Younis, W.; Asif, H.; Sharif, A.; Riaz, H.; Bukhari, I.A.; Assiri, A.M. Traditional medicinal plants used for respiratory disorders in Pakistan: A review of the ethno-medicinal and pharmacological evidence. Chin. Med., 2018, 13(1), 48.
[http://dx.doi.org/10.1186/s13020-018-0204-y] [PMID: 30250499]
[85]
Namukobe, J.; Kasenene, J.M.; Kiremire, B.T.; Byamukama, R.; Kamatenesi-Mugisha, M.; Krief, S.; Dumontet, V.; Kabasa, J.D. Traditional plants used for medicinal purposes by local communities around the Northern sector of Kibale National Park, Uganda. J. Ethnopharmacol., 2011, 136(1), 236-245.
[http://dx.doi.org/10.1016/j.jep.2011.04.044] [PMID: 21550390]
[86]
Mahmood, A.; Mahmood, A.; Naveed, I. Indigenous medicinal knowledge of common plants used by local people of Hattian Bala District, Azad Jammu and Kashmir (AJK), Pakistan. J. Med. Plants Res., 2011, 5(23), 5517-5521.
[87]
Niaz, S.; Bokhari, T.; Sherwani, S.; Younis, U.; Dasti, A. Ethnobotanical study of some medicinal plants of thal desert Punjab, Pakistan. Int. J. Pharm. Res. Biosci., 2013, 2, 31-41.
[88]
Kapahi, B.K.; Srivastava, T.N.; Sarin, Y.K. Traditional medicinal plants of gurez (kashmir) - an ethnobotanical study. Anc. Sci. Life, 1993, 13(1-2), 119-124.
[PMID: 22556637]
[89]
Savithramma, N.; Sulochana, C.; Rao, K.N. Ethnobotanical survey of plants used to treat asthma in Andhra Pradesh, India. J. Ethnopharmacol., 2007, 113(1), 54-61.
[http://dx.doi.org/10.1016/j.jep.2007.04.004] [PMID: 17606346]
[90]
Ullah, S.; Rashid Khan, M.; Ali Shah, N.; Afzal Shah, S.; Majid, M.; Asad Farooq, M. Ethnomedicinal plant use value in the Lakki Marwat District of Pakistan. J. Ethnopharmacol., 2014, 158(Pt A), 412-422.
[http://dx.doi.org/10.1016/j.jep.2014.09.048] [PMID: 25448507]
[91]
Hachicha, R.; Elleuch, F.; Ben Hlima, H.; Dubessay, P.; de Baynast, H.; Delattre, C.; Pierre, G.; Hachicha, R.; Abdelkafi, S.; Michaud, P.; Fendri, I. Biomolecules from microalgae and cyanobacteria: Applications and market survey. Appl. Sci., 2022, 12(4), 1924.
[http://dx.doi.org/10.3390/app12041924]
[92]
de Godos Crespo, I.; Álvaro, A.G.; Palomar, C.R.; Ibrahim, F.G.G.; Torre, R.M. Algal-Bacterial Consortiums, from Fundamental Interactions to Environmental Applications. In: Marine Organisms: A Solution to Environmental Pollution?; Springer, 2023, pp. 65-77.
[93]
Nimer, N.A. Nosocomial infection and antibiotic-resistant threat in the middle East. Infect. Drug Resist., 2022, 15, 631-639.
[http://dx.doi.org/10.2147/IDR.S351755] [PMID: 35241915]
[94]
Sharan, M.; Vijay, D.; Dhaka, P.; Bedi, J.S.; Gill, J.P.S. Biofilms as a microbial hazard in the food industry: A scoping review. J. Appl. Microbiol., 2022, 133(4), 2210-2234.
[http://dx.doi.org/10.1111/jam.15766] [PMID: 35945912]
[95]
Roy, H.; Bescos, R.; McColl, E.; Rehman, U.; Cray, E.; Belfield, L.A.; Nweze, K.D.; Tsang, K.; Singleton, W.; Whitfield, P.; Brookes, Z. Oral microbes and the formation of cerebral abscesses: A single-centre retrospective study. J. Dent., 2023, 128, 104366.
[http://dx.doi.org/10.1016/j.jdent.2022.104366] [PMID: 36402257]
[96]
Huang, L.; Huang, C.; Yan, Y.; Sun, L.; Li, H. Urinary tract infection etiological profiles and antibiotic resistance patterns varied among different age categories: A retrospective study from a tertiary general hospital during a 12-year period. Front. Microbiol., 2022, 12, 813145.
[http://dx.doi.org/10.3389/fmicb.2021.813145] [PMID: 35154037]
[97]
Sheikh, B.A.; Bhat, B.A.; Mir, M.A. Antimicrobial resistance: New insights and therapeutic implications. Appl. Microbiol. Biotechnol., 2022, 106(19-20), 6427-6440.
[http://dx.doi.org/10.1007/s00253-022-12175-8] [PMID: 36121484]
[98]
Iskandar, K.; Murugaiyan, J.; Hammoudi Halat, D.; Hage, S.E.; Chibabhai, V.; Adukkadukkam, S.; Roques, C.; Molinier, L.; Salameh, P.; Van Dongen, M. Antibiotic discovery and resistance: The chase and the race. Antibiotics, 2022, 11(2), 182.
[http://dx.doi.org/10.3390/antibiotics11020182] [PMID: 35203785]
[99]
Widmer, A.F. Emerging antibiotic resistance: Why we need new antibiotics! Swiss Med. Wkly., 2022, 152(4546), 40032.
[http://dx.doi.org/10.57187/smw.2022.40032] [PMID: 36351303]
[100]
Swami, D.; Anitha, M.; Rao, M.C.S.; Sharangi, A. Medicinal Plants: Perspectives And Retrospectives. In: Medicinal Plants; Apple Academic Press, 2022, pp. 1-28.
[101]
Bañuls, A.L.; Sanou, A.; Van Anh, N.T.; Godreuil, S. Mycobacterium tuberculosis: Ecology and evolution of a human bacterium. J. Med. Microbiol., 2015, 64(11), 1261-1269.
[http://dx.doi.org/10.1099/jmm.0.000171] [PMID: 26385049]
[102]
Gunn-Moore, D.A.; Jenkins, P.A.; Lucke, V.M. Feline tuberculosis: A literature review and discussion of 19 cases caused by an unusual mycobacterial variant. Vet. Rec., 1996, 138(3), 53-58.
[http://dx.doi.org/10.1136/vr.138.3.53] [PMID: 8629329]
[103]
Chaturvedi, A.K.; Verma, A.K.; Thakur, J.P.; Roy, S.; Bhushan Tripathi, S.; Kumar, B.S.; Khwaja, S.; Sachan, N.K.; Sharma, A.; Chanda, D.; Shanker, K.; Saikia, D.; Negi, A.S. A novel synthesis of 2-arylbenzimidazoles in molecular sieves-MeOH system and their antitubercular activity. Bioorg. Med. Chem., 2018, 26(15), 4551-4559.
[http://dx.doi.org/10.1016/j.bmc.2018.07.049] [PMID: 30097361]
[104]
WHO's Global Tuberculosis Report 2022. 2023. Report No.: 2666- 5247.
[105]
Lange, J.L. Bioaerosols: Molecular techniques for assessment and determinants of exposure in agriculture; The University of Iowa, 1996.
[106]
Ducati, R.G.; Ruffino-Netto, A.; Basso, L.A.; Santos, D.S. The resumption of consumption: A review on tuberculosis. Mem. Inst. Oswaldo Cruz, 2006, 101(7), 697-714.
[http://dx.doi.org/10.1590/S0074-02762006000700001] [PMID: 17160276]
[107]
Emmeluth, D.; Alcamo, I.E. Plague; Infobase Publishing, 2005.
[108]
Fogel, N. Tuberculosis: A disease without boundaries. Tuberculosis, 2015, 95(5), 527-531.
[http://dx.doi.org/10.1016/j.tube.2015.05.017] [PMID: 26198113]
[109]
Restrepo, B.I.; Schlesinger, L.S. Impact of diabetes on the natural history of tuberculosis. Diabetes Res. Clin. Pract., 2014, 106(2), 191-199.
[http://dx.doi.org/10.1016/j.diabres.2014.06.011] [PMID: 25082309]
[110]
Knechel, N.A. Tuberculosis: Pathophysiology, clinical features, and diagnosis. Crit. Care Nurse, 2009, 29(2), 34-43.
[http://dx.doi.org/10.4037/ccn2009968] [PMID: 19339446]
[111]
Caminero, J.A. Management of multidrug-resistant tuberculosis and patients in retreatment. Eur. Respir. J., 2005, 25(5), 928-936.
[http://dx.doi.org/10.1183/09031936.05.00103004] [PMID: 15863653]
[112]
Sandhu, G. Tuberculosis: Current situation, challenges and overview of its control programs in India. J. Glob. Infect. Dis., 2011, 3(2), 143-150.
[http://dx.doi.org/10.4103/0974-777X.81691] [PMID: 21731301]
[113]
Swartz, J. Substance Abuse in America: A documentary and reference guide: ABC-CLIO. 2012.
[114]
Rashid, A.; Akram, M.; Daniyal, M. Treatment strategies of multi-drug resistant mycobacterium tuberculosis. Pak. J. Med. Biol. Sci., 2017, 1(2)
[115]
Saifullah, B.; Hussein, M.Z.; Hussein Al Ali, S. Controlled-release approaches towards the chemotherapy of tuberculosis. Int. J. Nanomedicine, 2012, 7, 5451-5463.
[http://dx.doi.org/10.2147/IJN.S34996] [PMID: 23091386]
[116]
Zhang, D.; Lu, Y.; Liu, K.; Liu, B.; Wang, J.; Zhang, G.; Zhang, H.; Liu, Y.; Wang, B.; Zheng, M.; Fu, L.; Hou, Y.; Gong, N.; Lv, Y.; Li, C.; Cooper, C.B.; Upton, A.M.; Yin, D.; Ma, Z.; Huang, H. Identification of less lipophilic riminophenazine derivatives for the treatment of drug-resistant tuberculosis. J. Med. Chem., 2012, 55(19), 8409-8417.
[http://dx.doi.org/10.1021/jm300828h] [PMID: 22931472]
[117]
Dzoyem, J.P.; Hamamoto, H.; Ngameni, B.; Ngadjui, B.T.; Sekimizu, K. Antimicrobial action mechanism of flavonoids from Dorstenia species. Drug Discov. Ther., 2013, 7(2), 66-72.
[PMID: 23715504]
[118]
Mishra, D.K.; Shukla, S. A review on herbal treatment of tuberculosis. Int. Res. J. Pharm. Med. Sci., 2020, 3(5), 6-10.
[119]
Saukkonen, J.J.; Cohn, D.L.; Jasmer, R.M.; Schenker, S.; Jereb, J.A.; Nolan, C.M.; Peloquin, C.A.; Gordin, F.M.; Nunes, D.; Strader, D.B.; Bernardo, J.; Venkataramanan, R.; Sterling, T.R. An official ATS statement: Hepatotoxicity of antituberculosis therapy. Am. J. Respir. Crit. Care Med., 2006, 174(8), 935-952.
[http://dx.doi.org/10.1164/rccm.200510-1666ST] [PMID: 17021358]
[120]
Kanthamani, S; Narayanan, C; Venkataraman, K solation of lstachydrine and rutin from the fruits of Capparis moonii. semanticscholar, 1960, 409-411.
[121]
Kaura, T.; Sharmaa, P.; Guptac, G.K.; Ntie-Kangd, F.; Kumara, D. Treatment of tuberculosis by natural drugs: A review. Plant Arch., 2019, 19(2), 2168-2176.
[122]
Bueno, J.; Escobar, P.; Martínez, J.R.; Leal, S.M.; Stashenko, E.E. Composition of three essential oils, and their mammalian cell toxicity and antimycobacterial activity against drug resistant-tuberculosis and nontuberculous mycobacteria strains. Nat. Prod. Commun., 2011, 6(11)
[http://dx.doi.org/10.1177/1934578X1100601143]
[123]
Valcic, S.; Montenegro, G.; Mujica, A.M.; Avila, G.; Franzblau, S.; Singh, M.P.; Maiese, W.M.; Timmermann, B.N. Phytochemical, morphological, and biological investigations of propolis from Central Chile. Z. Naturforsch. C J. Biosci., 1999, 54(5-6), 406-416.
[http://dx.doi.org/10.1515/znc-1999-5-617] [PMID: 10431392]
[124]
Jackson, M.; McNeil, M.R.; Brennan, P.J. Progress in targeting cell envelope biogenesis in Mycobacterium tuberculosis. Future Microbiol., 2013, 8(7), 855-875.
[http://dx.doi.org/10.2217/fmb.13.52] [PMID: 23841633]
[125]
Balakrishnan, N.; Panda, A.; Raj, N.; Shrivastava, A.; Prathani, R. The evaluation of nitric oxide scavenging activity of Acalypha indica Linn root. Asian J. Res. Chem, 2009, 2(2), 148-150.
[126]
Mohan, C.; Dinakar, S.; Anand, T.; Elayaraja, R. Phytochemical, GC-MS analysis and Antibacterial activity of a Medicinal Plant Acalypha indica. Int. J. Pharm. Tech. Res., 2012, 4(3), 1050-1054.
[127]
Arya, V. A review on anti-tubercular plants. Int. J. Pharm. Tech. Res., 2011, 3, 872-880.
[128]
Shashidhar, M.; Sandhya, M.S.; Pankaj, P.; Suhasini, B. Herbal drugs as anti-tuberculosis agents. Int. J. Ayurvedic Herb. Med., 2015, 9, 1895-1900.
[129]
Lakshmi, T.; Roy, A.; Kaviya, N. Anti-tubercular herbal extracts used in Ayurveda-A mini review. Plant Cell Biotechnol. Mol. Biol., 2020, 54-60.
[130]
Apparao, M.; Kjær, A.; Olsen, O.; Rao, E.V.; Rasmussen, K.W.; Sørensen, H. Alliin in the garlicky taxon Adenocalymma alliaceum (Bignoniaceaei). Phytochemistry, 1981, 20(4), 822-823.
[http://dx.doi.org/10.1016/0031-9422(81)85185-0]
[131]
Aronchick, C.A.; Lipshutz, W.H.; Wright, S.H.; Dufrayne, F.; Bergman, G. A novel tableted purgative for colonoscopic preparation: Efficacy and safety comparisons with Colyte and Fleet Phospho-Soda. Gastrointest. Endosc., 2000, 52(3), 346-352.
[http://dx.doi.org/10.1067/mge.2000.108480] [PMID: 10968848]
[132]
Pengjam, Y.; Madhyastha, H.; Madhyastha, R.; Yamaguchi, Y.; Nakajima, Y.; Maruyama, M. Anthraquinone glycoside aloin induces osteogenic initiation of MC3T3-E1 cells: Involvement of MAPK mediated Wnt and Bmp signaling. Biomol. Ther., 2016, 24(2), 123-131.
[http://dx.doi.org/10.4062/biomolther.2015.106] [PMID: 26869456]
[133]
Basri, F.; Sharma, H.; Firdaus, S.; Jain, P.; Ranjan, A. A review of ethnomedicinal plant-Vitex negundo Linn. Int. J. Adv. Res., 2014, 2(3), 882-894.
[134]
Ahuja, S.; Ahuja, S.; Ahuja, U. Nirgundi (Vitex negundo)–Nature’s gift to mankind. Asian Agrihist., 2015, 19(1), 5-32.
[135]
Wang, Y.; Yang, L.; He, Y.Q.; Wang, C.H.; Welbeck, E.W.; Bligh, S.W.A.; Wang, Z.T. Characterization of fifty-one flavonoids in a Chinese herbal prescription Longdan Xiegan Decoction by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry and photodiode array detection. Rapid Commun. Mass Spectrom., 2008, 22(12), 1767-1778.
[http://dx.doi.org/10.1002/rcm.3536] [PMID: 18473331]
[136]
Bhattacharya, S.; Haldar, P.K. Protective role of the triterpenoid-enriched extract of Trichosanthes dioica root against experimentally induced pain and inflammation in rodents. Nat. Prod. Res., 2012, 26(24), 2348-2352.
[http://dx.doi.org/10.1080/14786419.2012.656111] [PMID: 22288562]
[137]
Ottaway, P.B. The technology of vitamins in food; Springer Science & Business Media, 2012.
[138]
Gopinath, R.; Manickan, E. Therapeutic Potentials of Medicinal plants against Mycobacterium tuberculosis (MTB) infections. ENVIS Newsletter., 2016, 14(4), 1-5.
[139]
Rai, P.K.; Mehta, S.; Gupta, R.K.; Watal, G. A novel antimicrobial agents Trichosanthes dioica. Int. J. Pharma Bio Sci., 2010, 1(3), 202-209.
[140]
Anandan, R.; Jayakar, B.; Karar, B.; Babuji, S.; Manavalan, R.; Kumar, R.S. Effect of ethanol extract of flowers of Vitex trifolia Linn. on CCL4 induced hepatic injury in rats. Pak. J. Pharm. Sci., 2009, 22(4), 391-394.
[PMID: 19783517]
[141]
Zanetti, S.; Cannas, S.; Molicotti, P. Evaluation of the antimicrobial properties of the essential oil of Myrtus communis L. against clinical strains of Mycobacterium spp. Interdiscip. Perspect. Infect. Dis., 2010, 2010, 931530.
[142]
Ghosal, S.; Biswas, K.; Chaudhuri, R.K. Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs. J. Pharm. Sci., 1978, 67(5), 721-722.
[http://dx.doi.org/10.1002/jps.2600670546] [PMID: 565403]
[143]
Bhatia, H.; Sharma, Y.P.; Manhas, R.K.; Kumar, K. Ethnomedicinal plants used by the villagers of district Udhampur, J&K, India. J. Ethnopharmacol., 2014, 151(2), 1005-1018.
[http://dx.doi.org/10.1016/j.jep.2013.12.017] [PMID: 24365639]
[144]
Sharma, S.; Kumar, M.; Sharma, S.; Nargotra, A.; Koul, S.; Khan, I.A. Piperine as an inhibitor of Rv1258c, a putative multidrug efflux pump of Mycobacterium tuberculosis. J. Antimicrob. Chemother., 2010, 65(8), 1694-1701.
[http://dx.doi.org/10.1093/jac/dkq186] [PMID: 20525733]
[145]
Tandon, V.R.; Khajuria, V.; Kapoor, B.; Kour, D.; Gupta, S. Hepatoprotective activity of Vitex negundo leaf extract against anti-tubercular drugs induced hepatotoxicity. Fitoterapia, 2008, 79(7-8), 533-538.
[http://dx.doi.org/10.1016/j.fitote.2008.05.005] [PMID: 18621114]
[146]
Gupta, V.K.; Shukla, C.; Bisht, G.R.S.; Saikia, D.; Kumar, S.; Thakur, R.L. Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay. Lett. Appl. Microbiol., 2011, 52(1), 33-40.
[http://dx.doi.org/10.1111/j.1472-765X.2010.02963.x] [PMID: 21114505]
[147]
Kim, J.; Rhee, C.K.; Yoo, K.H.; Kim, Y.S.; Lee, S.W.; Park, Y.B.; Lee, J.H.; Oh, Y.; Lee, S.D.; Kim, Y.; Kim, K.; Yoon, H. The health care burden of high grade chronic obstructive pulmonary disease in korea: AAnalysis of the korean health insurance review and assessment service data. Int. J. Chron. Obstruct. Pulmon. Dis., 2013, 8, 561-568.
[PMID: 24277985]
[148]
Mannino, D.M. Chronic obstructive pulmonary disease: Definition and epidemiology. Respir. Care, 2003, 48(12), 1185-1191.
[PMID: 14651759]
[149]
Improving the differential diagnosis of chronic obstructive pulmonary disease in primary care. Price, D.B.; Yawn, B.P; Jones, R.C., Ed.; Mayo Clinic Proceedings, 2010.
[150]
Vogelmeier, C.F.; Criner, G.J.; Martinez, F.J.; Anzueto, A.; Barnes, P.J.; Bourbeau, J.; Celli, B.R.; Chen, R.; Decramer, M.; Fabbri, L.M.; Frith, P.; Halpin, D.M.G.; López Varela, M.V.; Nishimura, M.; Roche, N.; Rodriguez-Roisin, R.; Sin, D.D.; Singh, D.; Stockley, R.; Vestbo, J.; Wedzicha, J.A.; Agustí, A. Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary. Am. J. Respir. Crit. Care Med., 2017, 195(5), 557-582.
[http://dx.doi.org/10.1164/rccm.201701-0218PP] [PMID: 28128970]
[151]
Kirkham, P.A.; Barnes, P.J. Oxidative Stress in COPD. Chest, 2013, 144(1), 266-273.
[http://dx.doi.org/10.1378/chest.12-2664] [PMID: 23880677]
[152]
Gonçalves, P.B.; Romeiro, N.C. Multi-target natural products as alternatives against oxidative stress in Chronic Obstructive Pulmonary Disease (COPD). Eur. J. Med. Chem., 2019, 163, 911-931.
[http://dx.doi.org/10.1016/j.ejmech.2018.12.020] [PMID: 30612088]
[153]
Domej, W.; Oetll, K.; Renner, W. Oxidative stress and free radicals in COPD – implications and relevance for treatment. Int. J. Chron. Obstruct. Pulmon. Dis., 2014, 9, 1207-1224.
[http://dx.doi.org/10.2147/COPD.S51226] [PMID: 25378921]
[154]
Baker, J.R.; Vuppusetty, C.; Colley, T.; Papaioannou, A.I.; Fenwick, P.; Donnelly, L.; Ito, K.; Barnes, P.J. Oxidative stress dependent microRNA-34a activation via PI3Kα reduces the expression of sirtuin-1 and sirtuin-6 in epithelial cells. Sci. Rep., 2016, 6(1), 35871.
[http://dx.doi.org/10.1038/srep35871] [PMID: 28442746]
[155]
Pant, M. Protection against cytotoxicity due to tobacco smoke by Adhatoda. Management, 2013, 1, 109-117.
[156]
Divya, K.; Tripathi, J.; Tiwari, S. Anti-Platelet Aggregating Activity of A Polyherbal Compound-Shirishadi-In Vitro Study. Biomed. Pharmacol. J., 2017, 10(2), 787-793.
[http://dx.doi.org/10.13005/bpj/1169]
[157]
Julius, A-GI; Charles, A Samuel, NE Nutraceutical with antiinflammatory activity for the Management of Airway Remodeling in bronchial asthma: Kalanchoe integra Var. Crenata (Andr.) Cuf leaf extrac Pharmacol Pharm., 2014.
[158]
Chong, L.; Zhang, W.; Nie, Y.; Yu, G.; Liu, L.; Lin, L.; Wen, S.; Zhu, L.; Li, C. Protective effect of curcumin on acute airway inflammation of allergic asthma in mice through Notch1-GATA3 signaling pathway. Inflammation, 2014, 37(5), 1476-1485.
[http://dx.doi.org/10.1007/s10753-014-9873-6] [PMID: 24706026]
[159]
Liu, B.; Yang, J.; Wen, Q.; Li, Y. Isoliquiritigenin, a flavonoid from licorice, relaxes guinea-pig tracheal smooth muscle In Vitro and In Vivo: Role of cGMP/PKG pathway. Eur. J. Pharmacol., 2008, 587(1-3), 257-266.
[http://dx.doi.org/10.1016/j.ejphar.2008.03.015] [PMID: 18462716]
[160]
Kajaria, D.; Pandey, B.L.; Tiwari, S.K.; Tripathi, J.S. Anti-histaminic, mast cell stabilizing and bronchodilator effect of hydroalcoholic extract of polyherbal compound- Bharangyadi. Anc. Sci. Life, 2012, 31(3), 95-100.
[http://dx.doi.org/10.4103/0257-7941.103182] [PMID: 23284214]
[161]
Gupta, S.K.; Prakash, J.; Srivastava, S. Validation of traditional claim of Tulsi, Ocimum sanctum Linn. as a medicinal plant. Indian J. Exp. Biol., 2002, 40(7), 765-773.
[PMID: 12597545]
[162]
Khushbu, C.; Roshni, S.; Anar, P.; Carol, M.; Mayuree, P. Phytochemical and therapeutic potential of Piper longum Linn a review. Int. J. Res. Ayurveda Pharm., 2011, 2(1), 157-161.
[163]
Vivean, P.R.; Kumar, V.; Manigandan, L.; Sasikala, M.; Parthibhan, P. Tylophora indica-A Mini Review. Int. J. Front Sci. Technol., 2014, 2, 58-66.
[164]
Adetunji, C.O.; Inobeme, A.; Olaniyan, O.T. Application of Nanodrugs Derived from Active Metabolites of Medicinal Plants for the Treatment of Inflammatory and Lung Diseases: Recent Advances; Med. Plants Lung Dis, 2021, pp. 609-622.
[165]
Inserra, P.; Brooks, A. Chapter 5 Getting to the Root of Chronic Inflammation: Ginger’s Antiinflammatory Properties. Nutr. Modulators Pain Aging Popul; Elsevier, 2017, pp. 67-73.
[http://dx.doi.org/10.1016/B978-0-12-805186-3.00005-9]
[166]
Dongre, P.R.; Bhujbal, S.S.; Kumar, D. Bronchodilatory activity of Curcuma longa, Zingiber officinale and Alpinia galanga based herbal formulation (AHF). Orient. Pharm. Exp. Med., 2015, 15(4), 341-346.
[http://dx.doi.org/10.1007/s13596-015-0205-7]
[167]
Horváth, G.; Ács, K. Essential oils in the treatment of respiratory tract diseases highlighting their role in bacterial infections and their anti-inflammatory action: A review. Flavour Fragrance J., 2015, 30(5), 331-341.
[http://dx.doi.org/10.1002/ffj.3252] [PMID: 32313366]
[168]
Irwin, R.S.; Madison, J.M. Symptom research on chronic cough: A historical perspective. Ann. Intern. Med., 2001, 134(9_Part_2), 809-814.
[http://dx.doi.org/10.7326/0003-4819-134-9_Part_2-200105011-00003] [PMID: 11346315]
[169]
Sultana, S.; Khan, A.; Safhi, M.M.; Alhazmi, H.A. Cough suppressant herbal drugs: A review. Int. J. Pharm. Sci. Invent., 2016, 5(5), 15-28.
[170]
Koufman, J.A. The Chronic Cough Enigma: How to recognize, diagnose and treat neurogenic and reflux related cough; Simon and Schuster, 2014.
[171]
Irwin, R.S.; Madison, J.M. The diagnosis and treatment of cough. N. Engl. J. Med., 2000, 343(23), 1715-1721.
[http://dx.doi.org/10.1056/NEJM200012073432308] [PMID: 11106722]
[172]
Gehr, P.; Annexe, A.; Annexe, A. Anatomy and morphology of the respiratory tract. Ann. ICRP, 1994, 24(1-3), 121-166.
[http://dx.doi.org/10.1016/0146-6453(94)90039-6]
[173]
Aviado, D.M., Jr; Schmidt, C.F. Reflexes from stretch receptors in blood vessels, heart and lungs. Physiol. Rev., 1955, 35(2), 247-300.
[http://dx.doi.org/10.1152/physrev.1955.35.2.247] [PMID: 14384508]
[174]
Fischer, B.; Voynow, J.; Ghio, A. COPD: Balancing oxidants and antioxidants. Int. J. Chron. Obstruct. Pulmon. Dis., 2015, 10, 261-276.
[http://dx.doi.org/10.2147/COPD.S42414] [PMID: 25673984]
[175]
Murry, T.; Carrau, R.L.; Chan, K. Clinical management of swallowing disorders; Plural Publishing, 2020.
[176]
Yoshida, S. Cough and Allergic Diseases. Absolute Allergy and Immunology Board Review; Springer, 2022, pp. 83-94.
[177]
Harkema, J.R.; Wagner, J.G. Pathology of the Respiratory System. In: Toxicologic Pathology for Non-Pathologists; Humana: New York, NY, 2019.
[http://dx.doi.org/10.1007/978-1-4939-9777-0_9]
[178]
Mutolo, D.; Iovino, L.; Cinelli, E.; Bongianni, F.; Pantaleo, T. Physiology of the Cough Reflex: Sensory and Mechanical Features. Cough: Pathophysiology, Diagnosis and Treatment; Springer: Cham, 2020, pp. 3-21.
[179]
Song, W.J.; Chung, K.F. Pharmacotherapeutic options for chronic refractory cough. Expert Opin. Pharmacother., 2020, 21(11), 1345-1358.
[http://dx.doi.org/10.1080/14656566.2020.1751816] [PMID: 32301356]
[180]
Wang, X.; Li, S.; Qu, H.; Hao, L.; Shao, T.; Wang, K.; Xia, Z.; Li, Z.; Li, Q. SERS-based immunomagnetic bead for rapid detection of H5N1 influenza virus. Influenza Other Respir. Viruses, 2023, 17(3), e13114.
[http://dx.doi.org/10.1111/irv.13114] [PMID: 36909299]
[181]
Esneau, C.; Duff, A.C.; Bartlett, N.W. Understanding rhinovirus circulation and impact on illness. Viruses, 2022, 14(1), 141.
[http://dx.doi.org/10.3390/v14010141] [PMID: 35062345]
[182]
Kaler, J.; Hussain, A.; Patel, K.; Hernandez, T.; Ray, S. Respiratory Syncytial Virus: A comprehensive review of transmission, pathophysiology, and manifestation. Cureus, 2023, 15(3), e36342.
[http://dx.doi.org/10.7759/cureus.36342] [PMID: 37082497]
[183]
Carbonetti, N. What causes the cough in whooping cough? MBio, 2022, 13(3), e00917-e00922.
[http://dx.doi.org/10.1128/mbio.00917-22] [PMID: 35604095]
[184]
Naqvi, K.F.; Mazzone, S.B.; Shiloh, M.U. Infectious and Inflammatory Pathways to Cough. Annu. Rev. Physiol., 2023, 85(1), 71-91.
[http://dx.doi.org/10.1146/annurev-physiol-031422-092315] [PMID: 36170660]
[185]
He, J.; Zhu, L.; Zhu, H.; Gu, X.; Li, P.; Yang, Y.; Yang, L. Dose selection of central or peripheral administration of sufentanil affect opioid induced cough?: A prospective, randomized, controlled trial. BMC Anesthesiol., 2018, 18(1), 38.
[http://dx.doi.org/10.1186/s12871-018-0502-z] [PMID: 29636004]
[186]
Grabczak, E.M.; Dabrowska, M.; Birring, S.S.; Krenke, R. Looking ahead to novel therapies for chronic cough. Part 1 – peripheral sensory nerve targeted treatments. Expert Rev. Respir. Med., 2020, 14(12), 1217-1233.
[http://dx.doi.org/10.1080/17476348.2020.1811686] [PMID: 32804594]
[187]
Erdei, A.; Benyhe, S.; Borsodi, A. Biochemical, functional and pharmacological characterization of novel bifunctional peptide ligands and nociceptin variants. New J. Chem., 2018, 42(8), 5656-5659.
[188]
Gunjan, M.; Naing, T.W.; Saini, R.S. Marketing trends & future prospects of herbal medicine in the treatment of various disease. World J. Pharm. Res., 2015, 4(9), 132-155.
[189]
Soudahmini, E.; Senthil, G.M.; Panayappan, L.; Divakar, M.C. Herbal remedies of Madugga tribes of Siruvani forest. South India. Nat. Prod. Radiance, 2005, 4(6), 492-501.
[190]
Adesina, S.K.; Johnny, I.I.; Olayiwola, G. Plants in respiratory disorders i-anti-asthmatics, a review. J. Pharm. Res. Int., 2017, 1-22.
[191]
Abouri, M.; El Mousadik, A.; Msanda, F. An ethnobotanical survey of medicinal plants used in the Tata Province, Morocco. Int. J. Med. Plants Res., 2012, 1(7), 99-123.
[192]
Kanchanapoom, T.; Ruchirawat, S. Megastigmane glucoside from Asystasia Gangetica (l.) t. anderson. J. Nat. Med., 2007, 61(4), 430-433.
[http://dx.doi.org/10.1007/s11418-007-0158-3]
[193]
Kumar, K.S.; Bhowmik, D. Traditional medicinal uses and therapeutic benefits of Momordica charantia Linn. Int. J. Pharm. Sci. Rev. Res., 2010, 4(3), 23-28.
[194]
Sharrif Moghaddasi, M.; Res, M. Aloe vera their chemicals composition and applications: A review. Int. J. Biol. Med. Res., 2011, 2(1), 466-471.
[195]
Banik, S.; Sharangi, A.B. Phytochemistry, health benefits and toxicological profile of aloe. J. Pharmacogn. Phytochem., 2019, 8(3), 4499-4506.
[196]
Srivastav, S.; Singh, P.; Mishra, G.; Jha, K.; Khosa, R. Achyranthes aspera-An important medicinal plant: A review. J. Nat. Prod. Plant Res., 2011, 1(1), 1-14.
[197]
McKenzie, S. Cough--but is it asthma? Arch. Dis. Child., 1994, 70(1), 1-2.
[http://dx.doi.org/10.1136/adc.70.1.1] [PMID: 8109998]
[198]
Kumar, D.; Prasad, D.; Parkash, J.; Bhatnagar, S.; Kumar, D. Antiasthmatic activity of ethanolic extract of Aerva lanata Linn. Pharmacologyonline, 2009, 2, 1075-1081.
[199]
Kumar, R.P.; Jindal, S.; Gupta, N.; Rana, R. An inside review of Amaranthus spinosus Linn: A potential medicinal plant of India. Int. J. Res. Pharm. Chem., 2014, 4(3), 643-653.
[200]
Alvarez, A.; Sanchez, C.; Garcia, D. Treatment of bronchial asthma with an aqueous extract of Mangifera indica L.(VIMANG®): Two cases report. Bol. Latinoam. Caribe Plantas Med. Aromat., 2009, 8(2), 63-66.
[201]
Ghuniyal, J. Ethanomedical, chemical, pharmacological, toxicological properties of Mangifera indica: A review. Int. J. Pharma Res. Rev., 2015, 4(10), 51-64.
[202]
Oghale, O.U.; Idu, M. Phytochemistry, anti-asthmatic and antioxidant activities of Anchomanes difformis (Blume) Engl. leaf extract. Asian Pac. J. Trop. Biomed., 2016, 6(3), 225-231.
[http://dx.doi.org/10.1016/j.apjtb.2015.12.007]
[203]
Meena, A.K.; Yadav, A.K.; Niranjan, U.S. A review on Calotropis procera Linn and its ethnobotany, phytochemical, pharmacological profile. Drug Invent Today., 2010, 2(2), 185-190.
[204]
Okunade, A.L. Ageratum conyzoides L. (Asteraceae). Fitoterapia, 2002, 73(1), 1-16.
[http://dx.doi.org/10.1016/S0367-326X(01)00364-1] [PMID: 11864757]
[205]
Kokwaro, J.O. Medicinal plants of east Africa; East African Literature Bureau, 1976.
[206]
Bartolome, A.P.; Villaseñor, I.M.; Yang, W-C. Bidens pilosa L. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology. Evid. Based Complement. Alternat. Med., 2013, 2013, 340215.
[207]
Jadhav, V.; Thorat, R.; Kadam, V.; Salaskar, K. Chemical composition, pharmacological activities of Eclipta alba. J. Pharm. Res., 2009, 2(8), 1129-1231.
[208]
Patel, M.B.; Panchal, S.J.; Patel, J.A. Antianaphylactic activity of alcoholic extract of Eclipta alba. J. Young Pharm., 2009, 1(3), 244.
[http://dx.doi.org/10.4103/0975-1483.57072]
[209]
Rahul, J. An ethnobotanical study of medicinal plants in Taindol village, district Jhansi, Region of Bundelkhand, Uttar Pradesh, India. Faslnamah-i Giyahan-i Daruyi, 2013, 1(5)
[210]
Chothani, D.; Vaghasiya, H.U. A review on Balanites aegyptiaca Del (desert date): Phytochemical constituents, traditional uses, and pharmacological activity. Pharmacogn. Rev., 2011, 5(9), 55-62.
[http://dx.doi.org/10.4103/0973-7847.79100] [PMID: 22096319]
[211]
Adesina, S.; Gbile, Z. Odukoya, O Survey of Indigenous Useful Plants of West Africa with Special Emphasis on Medicinal Plants and Issues Associated with Management; The United Nations Programme on Natural Resources in Africa, 1995, pp. 84-85.
[212]
Ebomoyi, M.; Okojie, A. Physiological mechanisms underlying the use of Garcinia kola Heckel in the treatment of asthma. African J. Respirat. Med., 2012, 8(1)
[213]
Eleyinmi, A.F.; Bressler, D.C.; Amoo, I.A.; Sporns, P.; Oshodi, A.A. Chemical composition of bitter cola (Garcinia kola) seed and hulls. Pol. J. Food Nutr. Sci., 2006, 15(4), 395.
[214]
Seanego, C.T.; Ndip, R.N. Identification and antibacterial evaluation of bioactive compounds from Garcinia kola (Heckel) seeds. Molecules, 2012, 17(6), 6569-6584.
[http://dx.doi.org/10.3390/molecules17066569] [PMID: 22728354]
[215]
Gangwar, A.K.; Ghosh, A.K. Medicinal uses and pharmacological activity of Adhatoda vasica. Int. J. Herb. Med., 2014, 2(1), 88-91.
[216]
Kumar, N. Pharmaceutical attributes of Vasa (Adhatoda vasica Linn.)-A review. World J. Pharm. Res., 2016, 5, 437-455.
[217]
Lone, S.H.; Jameel, S.; Bhat, M.A.; Lone, R.A.; Butcher, R.J.; Bhat, K.A. Synthesis of an unusual quinazoline alkaloid: Theoretical and experimental investigations of its structural, electronic, molecular and biological properties. RSC Advances, 2018, 8(15), 8259-8268.
[http://dx.doi.org/10.1039/C8RA00138C] [PMID: 35542000]
[218]
Bousquet, J.; Khaltaev, N.; Cruz, A.A.; Denburg, J.; Fokkens, W.J.; Togias, A.; Zuberbier, T.; Baena-Cagnani, C.E.; Canonica, G.W.; Van Weel, C.; Agache, I.; Aït-Khaled, N.; Bachert, C.; Blaiss, M.S.; Bonini, S.; Boulet, L.P.; Bousquet, P.J.; Camargos, P.; Carlsen, K.H.; Chen, Y.; Custovic, A.; Dahl, R.; Demoly, P.; Douagui, H.; Durham, S.R.; Van Wijk, R.G.; Kalayci, O.; Kaliner, M.A.; Kim, Y.Y.; Kowalski, M.L.; Kuna, P.; Le, L.T.T.; Lemiere, C.; Li, J.; Lockey, R.F.; Mavale-Manuel, S.; Meltzer, E.O.; Mohammad, Y.; Mullol, J.; Naclerio, R.; O’Hehir, R.E.; Ohta, K.; Ouedraogo, S.; Palkonen, S.; Papadopoulos, N.; Passalacqua, G.; Pawankar, R.; Popov, T.A.; Rabe, K.F.; Rosado-Pinto, J.; Scadding, G.K.; Simons, F.E.R.; Toskala, E.; Valovirta, E.; Van Cauwenberge, P.; Wang, D.Y.; Wickman, M.; Yawn, B.P.; Yorgancioglu, A.; Yusuf, O.M.; Zar, H.; Annesi-Maesano, I.; Bateman, E.D.; Kheder, A.B.; Boakye, D.A.; Bouchard, J.; Burney, P.; Busse, W.W.; Chan-Yeung, M.; Chavannes, N.H.; Chuchalin, A.; Dolen, W.K.; Emuzyte, R.; Grouse, L.; Humbert, M.; Jackson, C.; Johnston, S.L.; Keith, P.K.; Kemp, J.P.; Klossek, J.M.; Larenas-Linnemann, D.; Lipworth, B.; Malo, J.L.; Marshall, G.D.; Naspitz, C.; Nekam, K.; Niggemann, B.; Nizankowska-Mogilnicka, E.; Okamoto, Y.; Orru, M.P.; Potter, P.; Price, D.; Stoloff, S.W.; Vandenplas, O.; Viegi, G.; Williams, D. Allergic rhinitis and its impact on asthma (ARIA) 2008. Allergy, 2008, 63(86), 8-160.
[http://dx.doi.org/10.1111/j.1398-9995.2007.01620.x] [PMID: 18331513]
[219]
Robinson, D.; Humbert, M.; Buhl, R.; Cruz, A.A.; Inoue, H.; Korom, S.; Hanania, N.A.; Nair, P. Revisiting Type 2-high and Type 2-low airway inflammation in asthma: Current knowledge and therapeutic implications. Clin. Exp. Allergy, 2017, 47(2), 161-175.
[http://dx.doi.org/10.1111/cea.12880] [PMID: 28036144]
[220]
Folli, C.; Descalzi, D.; Scordamaglia, F.; Riccio, A.M.; Gamalero, C.; Canonica, G.W. New insights into airway remodelling in asthma and its possible modulation. Curr. Opin. Allergy Clin. Immunol., 2008, 8(5), 367-375.
[http://dx.doi.org/10.1097/ACI.0b013e32830a7086] [PMID: 18769186]
[221]
Boxall, C.; Holgate, S.T.; Davies, D.E. The contribution of transforming growth factor- and epidermal growth factor signalling to airway remodelling in chronic asthma. Eur. Respir. J., 2006, 27(1), 208-229.
[http://dx.doi.org/10.1183/09031936.06.00130004] [PMID: 16387953]
[222]
Amaral-Machado, L.; Oliveira, W.N.; Moreira-Oliveira, S.S. Use of Natural Products in Asthma Treatment. Evid. Based Complement. Alternat. Med., 2020, 2020, 1021258.
[http://dx.doi.org/10.1155/2020/1021258]
[223]
Nirmal, S.A.; Pal, S.C.; Mandal, S.C. Mast cell stabilizing and bronchodilatory activity of Nyctanthes arbortristis bark. Phytopharmacology., 2012, 2(1), 234-242.
[224]
Channa, S.; Dar, A.; Yaqoob, M.; Anjum, S.; Sultani, Z.; Rahman, A. Broncho-vasodilatory activity of fractions and pure constituents isolated from Bacopa monniera. J. Ethnopharmacol., 2003, 86(1), 27-35.
[http://dx.doi.org/10.1016/S0378-8741(03)00013-8] [PMID: 12686438]
[225]
de Melo, I.C.A.R.; de Souza, I.L.L.; Vasconcelos, L.H.C.; Scotti, M.T.; da Silva, B.A.; Schripsema, J.; Fonseca, A.H.; Oliveira, E.J. Metabolomic fingerprinting of Cissampelos Sympodialis eichler leaf extract and correlation with its spasmolytic activity. J. Ethnopharmacol., 2020, 253, 112678.
[http://dx.doi.org/10.1016/j.jep.2020.112678] [PMID: 32087317]
[226]
Kumar, A.P.; Nishteswar, K. Phytochemical and pharmacological profiles of Clerodendrum Serratum linn.(bharngi): A review. Int. J. Res. Ayurveda Pharm., 2013, 4(2), 276-278.
[http://dx.doi.org/10.7897/2277-4343.04239]
[227]
Mali, R.G.; Dhake, A.S. A review on herbal antiasthmatics. Orient. Pharm. Exp. Med., 2011, 11(2), 77-90.
[http://dx.doi.org/10.1007/s13596-011-0019-1] [PMID: 22207824]
[228]
Tang, J.; Sun, J.; Zhang, Y.; Li, L.; Cui, F.; He, Z. Herb–drug interactions: Effect of Ginkgo biloba extract on the pharmacokinetics of theophylline in rats. Food Chem. Toxicol., 2007, 45(12), 2441-2445.
[http://dx.doi.org/10.1016/j.fct.2007.05.023] [PMID: 17681658]
[229]
Abrika, O.S.S.; Yam, M.F.; Asmawi, M.Z.; Sadikun, A.; Dieng, H.; Hussain, E.A. Effects of extracts and fractions of Gynura procumbens on rat atrial contraction. J. Acupunct. Meridian Stud., 2013, 6(4), 199-207.
[http://dx.doi.org/10.1016/j.jams.2013.01.020] [PMID: 23972242]
[230]
Roja, G.; Vikrant, B.H.; Sandur, S.K.; Sharma, A.; Pushpa, K.K. Accumulation of vasicine and vasicinone in tissue cultures of Adhatoda vasica and evaluation of the free radical-scavenging activities of the various crude extracts. Food Chem., 2011, 126(3), 1033-1038.
[http://dx.doi.org/10.1016/j.foodchem.2010.11.115]
[231]
Qadir, M.I.; Abbas, K.; Younus, A. Shaikh, R.S. Report - Antibacterial activity of sea buckthorn (Hippophae rhamnoides L.) against methicillin resistant Staphylococcus aureus (MRSA). Pak. J. Pharm. Sci., 2016, 29(5), 1711-1713.
[PMID: 27731833]
[232]
Tirpude, N.V.; Sharma, A.; Joshi, R.; Kumari, M.; Acharya, V. Vitex negundo Linn. extract alleviates inflammatory aggravation and lung injury by modulating AMPK/PI3K/Akt/p38-NF-κB and TGF-β/Smad/Bcl2/caspase/LC3 cascade and macrophages activation in murine model of OVA-LPS induced allergic asthma. J. Ethnopharmacol., 2021, 271, 113894.
[http://dx.doi.org/10.1016/j.jep.2021.113894] [PMID: 33516930]
[233]
Matsumoto, M.; Hirayama, M.; Ohtomi, N.; Ohno, T.; Nomura, Y.; Iida, O.; Sugimura, K.; Kawahara, N.; Tsuchida, T.; Mikage, M. Influence of genetic factors on the ephedrine alkaloid composition ratio of Ephedra plants. J. Nat. Med., 2015, 69(1), 63-67.
[http://dx.doi.org/10.1007/s11418-014-0863-7] [PMID: 25115226]
[234]
Priyashree, S.; Jha, S.; Pattanayak, S.P. Bronchodilatory and mast cell stabilising activity of Cressa cretica L.: Evaluation through In Vivo and In Vitro experimental models. Asian Pac. J. Trop. Med., 2012, 5(3), 180-186.
[http://dx.doi.org/10.1016/S1995-7645(12)60021-2] [PMID: 22305781]
[235]
Sumathi, T.; Niranjali Devaraj, S. Effect of Bacopa monniera on liver and kidney toxicity in chronic use of opioids. Phytomedicine, 2009, 16(10), 897-903.
[http://dx.doi.org/10.1016/j.phymed.2009.03.005] [PMID: 19403290]
[236]
Shin, T.Y.; Kim, D.K. Inhibitory effect of mast cell-dependent anaphylaxis by Gleditsia sinensis. Arch. Pharm. Res., 2000, 23(4), 401-406.
[http://dx.doi.org/10.1007/BF02975455] [PMID: 10976591]
[237]
Sahare, K.N.; Singh, V. Antifilarial activity of ethyl acetate extract of Vitex negundo leaves In Vitro. Asian Pac. J. Trop. Med., 2013, 6(9), 689-692.
[http://dx.doi.org/10.1016/S1995-7645(13)60119-4] [PMID: 23827144]
[238]
QSAR model for mast cell stabilizing activity of indolecarboxamidotetrazole compounds on human basophils. Basu, A.; Sarkar, A.; Basak, P., Eds.; International Conference on Computational Intelligence, Communications, and Business Analytics, 2017.
[http://dx.doi.org/10.1007/978-981-10-6430-2_2]
[239]
Palbag, S.; Dey, B.K.; Singh, N.K. Ethnopharmacology, phytochemistry and pharmacology of Tephrosia purpurea. Chin. J. Nat. Med., 2014, 12(1), 1-7.
[http://dx.doi.org/10.1016/S1875-5364(14)60001-7] [PMID: 24484589]
[240]
Singh, R.K.; Bhattacharya, S.K.; Acharya, S.B. Studies on extracts of Elaeocarpus sphaericus fruits on In Vitro rat mast cells. Phytomedicine, 2000, 7(3), 205-207.
[http://dx.doi.org/10.1016/S0944-7113(00)80005-7] [PMID: 11185731]
[241]
Sadeghnia, H.R.; Jamshidi, R.; Afshari, A.R.; Mollazadeh, H.; Forouzanfar, F.; Rakhshandeh, H. Terminalia chebula attenuates quinolinate-induced oxidative PC12 and OLN-93 cell death. Mult. Scler. Relat. Disord., 2017, 14, 60-67.
[http://dx.doi.org/10.1016/j.msard.2017.03.012] [PMID: 28619434]
[242]
Kim, Y.C.; Lee, E.H.; Lee, Y.M.; Kim, H.K.; Song, B.K.; Lee, E.J.; Kim, H.M. Effect of the aqueous extract of Aquilaria agallocha stems on the immediate hypersensitivity reactions. J. Ethnopharmacol., 1997, 58(1), 31-38.
[http://dx.doi.org/10.1016/S0378-8741(97)00075-5] [PMID: 9324002]
[243]
Pan, Z.; Fang, Z.; Lu, W.; Liu, X.; Zhang, Y. Osthole, a coumadin analog from Cnidium monnieri (L.) Cusson, stimulates corticosterone secretion by increasing steroidogenic enzyme expression in mouse Y1 adrenocortical tumor cells. J. Ethnopharmacol., 2015, 175, 456-462.
[http://dx.doi.org/10.1016/j.jep.2015.10.009] [PMID: 26456364]
[244]
Goyal, B.R.; Agrawal, B.B.; Goyal, R.K.; Mehta, A.A. Pharmacological classification of herbal anti-asthmatics. Orient. Pharm. Exp. Med., 2007, 7(1), 11-25.
[http://dx.doi.org/10.3742/OPEM.2007.7.1.011]
[245]
Zhao, X.; Wang, C.; Meng, H.; Yu, Z.; Yang, M.; Wei, J. Dalbergia odorifera: A review of its traditional uses, phytochemistry, pharmacology, and quality control. J. Ethnopharmacol., 2020, 248, 112328.
[http://dx.doi.org/10.1016/j.jep.2019.112328] [PMID: 31654799]
[246]
Agarwal, R.; Diwanay, S.; Patki, P.; Patwardhan, B. Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation. J. Ethnopharmacol., 1999, 67(1), 27-35.
[http://dx.doi.org/10.1016/S0378-8741(99)00065-3] [PMID: 10616957]
[247]
Vetal, S.; Bodhankar, S.L.; Mohan, V.; Thakurdesai, P.A. Anti-inflammatory and anti-arthritic activity of type-A procyanidine polyphenols from bark of Cinnamomum zeylanicum in rats. Food Sci. Hum. Wellness, 2013, 2(2), 59-67.
[http://dx.doi.org/10.1016/j.fshw.2013.03.003]
[248]
Ramachandran, S.; Sridhar, Y.; Kishore Gnana Sam, S.; Saravanan, M.; Thomas Leonard, J.; Anbalagan, N.; Sridhar, S.K. Aphrodisiac activity of Butea frondosa Koen. ex Roxb. extract in male rats. Phytomedicine, 2004, 11(2-3), 165-168.
[http://dx.doi.org/10.1078/0944-7113-00343] [PMID: 15070167]
[249]
Baldé, E.S.; Megalizzi, V.; Traoré, M.S.; Cos, P.; Maes, L.; Decaestecker, C.; Pieters, L.; Baldé, A.M. In Vitro antiprotozoal, antimicrobial and antitumor activity of Pavetta crassipes K. Schum leaf extracts. J. Ethnopharmacol., 2010, 130(3), 529-535.
[http://dx.doi.org/10.1016/j.jep.2010.05.042] [PMID: 20561931]
[250]
Owoyele, V.B.; Oloriegbe, Y.Y.; Balogun, E.A.; Soladoye, A.O. Analgesic and anti-inflammatory properties of Nelsonia canescens leaf extract. J. Ethnopharmacol., 2005, 99(1), 153-156.
[http://dx.doi.org/10.1016/j.jep.2005.02.003] [PMID: 15848036]
[251]
Hung, T.M.; Thu, C.V.; Dat, N.T.; Ryoo, S.W.; Lee, J.H.; Kim, J.C.; Na, M.; Jung, H.J.; Bae, K.; Min, B.S. Homoisoflavonoid derivatives from the roots of Ophiopogon japonicus and their In Vitro anti-inflammation activity. Bioorg. Med. Chem. Lett., 2010, 20(8), 2412-2416.
[http://dx.doi.org/10.1016/j.bmcl.2010.03.043] [PMID: 20346658]
[252]
Nourozi, E.; Hosseini, B.; Maleki, R.; Mandoulakani, B.A. Pharmaceutical important phenolic compounds overproduction and gene expression analysis in Dracocephalum kotschyi hairy roots elicited by SiO2 nanoparticles. Ind. Crops Prod., 2019, 133, 435-446.
[http://dx.doi.org/10.1016/j.indcrop.2019.03.053]
[253]
Bhattacherjee, A.K.; Dikshit, A.; Pandey, D.; Tandon, D.K. High performance liquid chromatographic determination of marmelosin and psoralen in bael (Aegle marmelos (L.) Correa) fruit. J. Food Sci. Technol., 2015, 52(1), 597-600.
[http://dx.doi.org/10.1007/s13197-013-1015-x]
[254]
Russo, A.; Cardile, V.; Graziano, A.C.E.; Avola, R.; Montenegro, I.; Cuellar, M.; Villena, J.; Madrid, A. Antigrowth activity and induction of apoptosis in human melanoma cells by Drymis winteri forst extract and its active components. Chem. Biol. Interact., 2019, 305, 79-85.
[http://dx.doi.org/10.1016/j.cbi.2019.03.029] [PMID: 30935903]
[255]
Rahimi, R.; Ghiasi, S.; Azimi, H.; Fakhari, S.; Abdollahi, M. A review of the herbal phosphodiesterase inhibitors; Future perspective of new drugs. Cytokine, 2010, 49(2), 123-129.
[http://dx.doi.org/10.1016/j.cyto.2009.11.005] [PMID: 20005737]
[256]
Perez-Hernandez, N.; Ponce-Monter, H.; Medina, J.A.; Joseph-Nathan, P. Spasmolytic effect of constituents from Lepechinia caulescens on rat uterus. J. Ethnopharmacol., 2008, 115(1), 30-35.
[http://dx.doi.org/10.1016/j.jep.2007.08.044] [PMID: 17997242]
[257]
Prasanth Reddy, V.; Ravi Vital, K.; Varsha, P.; Satyam, S. Review on Thymus vulgaris traditional uses and pharmacological properties. Med. Aromat. Plants, 2014, 3(164), 2167.
[258]
Pavlović, I.; Petrović, S.; Radenković, M.; Milenković, M.; Couladis, M.; Branković, S.; Drobac, M.P.; Niketić, M. Composition, antimicrobial, antiradical and spasmolytic activity of Ferula heuffelii Griseb. ex Heuffel (Apiaceae) essential oil. Food Chem., 2012, 130(2), 310-315.
[http://dx.doi.org/10.1016/j.foodchem.2011.07.043]
[259]
Wang, X.; Hai, C.X.; Liang, X.; Yu, S.X.; Zhang, W.; Li, Y.L. The protective effects of Acanthopanax senticosus Harms aqueous extracts against oxidative stress: Role of Nrf2 and antioxidant enzymes. J. Ethnopharmacol., 2010, 127(2), 424-432.
[http://dx.doi.org/10.1016/j.jep.2009.10.022] [PMID: 19857565]
[260]
Heo, Y.; Cho, Y.; Ju, K.; Cho, H.; Park, K.H.; Choi, H.; Yoon, J.K.; Moon, C.; Kim, Y.B. Antiviral activity of Poncirus trifoliata seed extract against oseltamivir-resistant influenza virus. J. Microbiol., 2018, 56(8), 586-592.
[http://dx.doi.org/10.1007/s12275-018-8222-0] [PMID: 30047088]
[261]
Okpo, S.O.; Adeyemi, O.O. The antianaphylactic effects of Crinum glaucum aqueous extract. J. Ethnopharmacol., 2002, 81(2), 187-190.
[http://dx.doi.org/10.1016/S0378-8741(02)00050-8] [PMID: 12065149]
[262]
Taur, D.J.; Patil, R.Y. Some medicinal plants with antiasthmatic potential: A current status. Asian Pac. J. Trop. Biomed., 2011, 1(5), 413-418.
[http://dx.doi.org/10.1016/S2221-1691(11)60091-9] [PMID: 23569804]
[263]
Lee, H.T.; Seo, E.K.; Chung, S.J.; Shim, C.K. Prokinetic activity of an aqueous extract from dried immature fruit of Poncirus trifoliata (L.). Raf. J. Ethnopharmacol., 2005, 102(2), 131-136.
[http://dx.doi.org/10.1016/j.jep.2005.05.052] [PMID: 16191468]
[264]
Hong, S.H.; Jeong, H.J.; Kim, H.M. Inhibitory effects of Xanthii fructus extract on mast cell-mediated allergic reaction in murine model. J. Ethnopharmacol., 2003, 88(2-3), 229-234.
[http://dx.doi.org/10.1016/S0378-8741(03)00232-0] [PMID: 12963148]
[265]
Sashidhara, K.V.; Rosaiah, J.N.; Kumar, A.; Bid, H.K.; Konwar, R.; Chattopadhyay, N. Cell growth inhibitory action of an unusual labdane diterpene, 13- epi -sclareol in breast and uterine cancers In Vitro. Phytother. Res., 2007, 21(11), 1105-1108.
[http://dx.doi.org/10.1002/ptr.2205] [PMID: 17639552]
[266]
Khan, M.A.; Ali, R.; Parveen, R.; Najmi, A.K.; Ahmad, S. Pharmacological evidences for cytotoxic and antitumor properties of Boswellic acids from Boswellia serrata. J. Ethnopharmacol., 2016, 191, 315-323.
[http://dx.doi.org/10.1016/j.jep.2016.06.053] [PMID: 27346540]
[267]
Momohara, A.; Yoshida, A.; Kudo, Y.; Nishiuchi, R.; Okitsu, S. Paleovegetation and climatic conditions in a refugium of temperate plants in central Japan in the Last Glacial Maximum. Quat. Int., 2016, 425, 38-48.
[http://dx.doi.org/10.1016/j.quaint.2016.07.001]
[268]
Nardella, F.; Gallé, J-B.; Bourjot, M.; Weniger, B.; Vonthron-Sénécheau, C. Antileishmanial and antitrypanosomal activities of flavonoids In: Natural Antimicrobial Agents. Sustainable Development and Biodiversity; Springer: Cham, 2018, 19, pp. 163-194.
[269]
Gautam, R.; Jachak, S.M. Recent developments in anti-inflammatory natural products. Med. Res. Rev., 2009, 29(5), 767-820.
[http://dx.doi.org/10.1002/med.20156] [PMID: 19378317]
[270]
Kao, E.S.; Wang, C.J.; Lin, W.L.; Yin, Y.F.; Wang, C.P.; Tseng, T.H. Anti-inflammatory potential of flavonoid contents from dried fruit of Crataegus pinnatifida In Vitro and In Vivo. J. Agric. Food Chem., 2005, 53(2), 430-436.
[http://dx.doi.org/10.1021/jf040231f] [PMID: 15656684]
[271]
Lombard, N.; Le Roux, M.M.; Van Wyk, B.E. Thesium ovatifolium (Santalaceae), a new species with ovate leaves from KwaZulu-Natal, South Africa. Phytotaxa, 2019, 405(5), 263-268.
[http://dx.doi.org/10.11646/phytotaxa.405.5.5]
[272]
Lipinski, C.A.; Lombardo, F.; Dominy, B.W.; Feeney, P.J. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1. Adv. Drug Deliv. Rev., 2001, 46(1-3), 3-26.
[http://dx.doi.org/10.1016/S0169-409X(00)00129-0] [PMID: 11259830]
[273]
Veber, D.F.; Johnson, S.R.; Cheng, H.Y.; Smith, B.R.; Ward, K.W.; Kopple, K.D. Molecular properties that influence the oral bioavailability of drug candidates. J. Med. Chem., 2002, 45(12), 2615-2623.
[http://dx.doi.org/10.1021/jm020017n] [PMID: 12036371]
[274]
Daina, A.; Michielin, O.; Zoete, V. SwissADME: A free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules. Sci. Rep., 2017, 7(1), 42717.
[http://dx.doi.org/10.1038/srep42717] [PMID: 28256516]

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