Title:A Comprehensive Review of Herbal Medicines for the Treatment of
Alzheimer's Disease
Volume: 10
Issue: 5
Author(s): Sumbul Shadab, GSN Koteswara Rao*, Deepika Paliwal, Devdhar Yadav, Aftab Alam, Amit Singh and Md Jaha Sultana
Affiliation:
- Department of Pharmacy, School of Medical & Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh,
India
- Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, V.L. Mehta
Road, Vile Parle (W), Mumbai, 400056, India
Keywords:
Alzheimer’s disease, cerebral blood flow, memory, medicinal plants, active component, seniles plaque.
Abstract: The choices of treatment for Alzheimer's are based on NMDA-receptor antagonists and
cholinesterase inhibitors, although their efficacy as a therapy is still up for debate. BPSD (Behavioural
and Psychological Symptoms of Dementia) have been treated using herbal medicine products,
with varying degrees of success. This manuscript sets out to answer the question, "Can herbs
be effective in the treatment of cognitive impairments in patients?" by examining evidences from
controlled research. The process by which Alzheimer's disease develops remains a mystery, and the
present Alzheimer's treatment strategy, which consists of administering a single medicine to treat a
single target, appears to be clinically ineffective. AD treatment will require a combination of approaches
that target many signs and causes of the disease. The results of currently available licensed
therapies for AD are often disappointing, and alternative medicine, especially herbal therapy, may
play a role. Over 80% of the world's population, particularly in developing nation, gets their main
health care from herbal medicines. They have persisted through the years due to their low risk, high
reward, widespread acceptance across cultures, and absence of detrimental side effects. In some
cases, herbal remedies have proven to be more effective than conventional medical treatments. They
are assumed to be natural unless proven otherwise by the presence of unnatural additives. The absence
of adverse reactions is a major advantage of herbal treatment. In addition, they provide ongoing
advantages to health. Salvia officinalis, Ginkgo biloba, Melissa officinalis, Panax ginseng, Coriandrum
sativum, Curcuma longa, Ashwagandha, Uncaria Tomentosa, Crocus Sativus and Allium
Sativum are all studied for their potential effects on Alzheimer's disease.