Title:Recent Advances in Organic Synthesis Using Glycerol as a Green Media
Volume: 20
Issue: 10
Author(s): Kereyagalahally H. Narasimhamurthy, Muthipeedika Nibin Joy, Ayyiliath M. Sajith, Sougata Santra, Grigory V. Zyryanov, Toreshettahally R. Swaroop*Kanchugarakoppal S. Rangappa*
Affiliation:
- Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysuru, 570006, Karnataka
India
- Vignana Bhavana, University of Mysore, Manasagangotri, Mysuru, 570006, Karnataka, India
Keywords:
Green chemistry, glycerol, catalyst-free, synthesis, green media, cyclization.
Abstract: Various catalytic and non-catalytic organic transformations are carried out in glycerol media
with superior efficiency over commonly employed organic solvents. The success of glycerol as a
green media is due to its exceptional H-bonding properties, which result in enhanced reactivity in
many organic transformations. In addition, its highly polar nature and non-toxic properties, recyclability,
large availability as an organic waste from the biodiesel industry, high boiling point, low vapor
pressure and low price further extend the scope of this solvent as green media. In this review, we present
the potential use of glycerol as a green solvent in many organic transformations in two sections:
cyclization reactions and miscellaneous reactions.