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Review Article

药物应用的肽类两亲分子

卷 31, 期 11, 2024

发表于: 23 May, 2023

页: [1332 - 1347] 页: 16

弟呕挨: 10.2174/0929867330666230408203820

价格: $65

Open Access Journals Promotions 2
摘要

在过去的几十年里，人们为开发生物相容性材料做出了一些努力。其中，肽类两亲体(PAs)具有组织特异性结合和定位功能，是生物医学领域应用的一种新型纳米技术策略。PAs具有几个结合疏水和亲水区域的区域，这些区域能够在水介质中自组装，形成能够与细胞膜相互作用的不同三级纳米结构。此外，这些分子可以通过加入胶原蛋白、脂质或荧光标记物来调节。此外，它们还可以作为载体，以包封活性化合物用于药物递送，在这一领域显示出很好的特点。本文就PAs的自组装结构及其药理应用作一综述。此外，还强调了它们作为药物输送系统的用途，并对该领域的最新进展进行了综述。

关键词: 肽两亲体，纳米技术，药物传递，抗菌，抗癌，超分子自组装，纳米结构。

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