摘要
背景:在2019冠状病毒病大流行期间,人们遭受了严重的精神健康问题。这些症状包括压力、焦虑和对居家隔离现状的困惑。褪黑素是一种流行的抗炎和抗氧化分子,作为非处方膳食补充剂出售。 目的:本文综述了在COVID-19大流行背景下使用褪黑素的适应症,包括治疗。 方法:在电子数据库中全面检索有关COVID-19患者褪黑素使用的出版物。 结果:压力对睡眠规律和个人生活质量有巨大的负面影响。睡眠被认为是免疫反应的重要调节剂。因此,睡眠不足会削弱免疫力,增加机体对感染的易感性。例如,较短的睡眠时间与患普通感冒的几率增加有关。褪黑素的管理可以防止病毒和其他病原体,并加快临床恢复。 结论:在重症监护病房的患者中,褪黑素降低了血栓和败血症等严重并发症的风险和死亡率。此外,它还能有效降低血管通透性、抑制和镇静,改善睡眠质量,这也有助于COVID-19患者获得更好的临床效果。
关键词: COVID-19、褪黑素、膳食补充剂、睡眠质量、抗氧化剂、压力。
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