Title:Recent Advances on the Antimicrobial Activities of Schiff Bases and
their Metal Complexes: An Updated Overview
Volume: 31
Issue: 17
关键词:
希夫氏碱,抗菌活性,亚胺,亚甲基,抗菌,抗真菌,抗病毒,抗疟疾。
摘要: Schiff bases represent a valuable class of organic compounds, synthesized via
condensation of primary amines with ketones or aldehydes. They are renowned for possessing
innumerable applications in agricultural chemistry, organic synthesis, chemical
and biological sensing, coating, polymer and resin industries, catalysis, coordination
chemistry, and drug designing. Schiff bases contain imine or azomethine (-C=N-) functional
groups which are important pharmacophores for the design and synthesis of lead
bioactive compounds. In medicinal chemistry, Schiff bases have attracted immense attention
due to their diverse biological activities. This review aims to encompass the recent
developments on the antimicrobial activities of Schiff bases. The article summarizes the
antibacterial, antifungal, antiviral, antimalarial, and antileishmanial activities of Schiff bases
reported since 2011.