Title:Perspective and Prospects on Persistent Luminescent Nanoparticles
for Biological Imaging and Tumor Therapy
Volume: 31
Issue: 8
Author(s): Minghui Sun, Ming Chen*Jun Wang*
Affiliation:
- Department of Clinical Laboratory Medicine, Southwest Hospital, Army Medical University, 30 Gaotanyan,
Shapingba District, Chongqing 400038, China
- Department of Clinical Laboratory Medicine, Southwest Hospital, Army Medical University, 30 Gaotanyan,
Shapingba District, Chongqing 400038, China
Keywords:
Persistent luminescent nanoparticles, synthetic method, afterglow, optical imaging, biological imaging, imaging-guided therapy.
Abstract: Persistent luminescent nanoparticles (PLNPs) are photoluminescent materials
that can still emit luminescence after the cessation of the excitation light source. In recent
years, due to their unique optical properties, the PLNPs have attracted extensive attention
in the biomedical field. Since the PLNPs effectively eliminate autofluorescence interference
from biological tissues, many researchers have contributed a lot of work in the
fields of biological imaging and tumor therapy. This article mainly introduces the synthesis
methods of the PLNPs and their progress in the application of biological imaging and
tumor therapy, as well as the challenges and development prospects.