Title:Recurrent Nausea and Vomiting with Weight Loss Associated with Hypothyroidism:
Fact or Myth
Volume: 23
Issue: 6
Author(s): Jitendra Singh*, Anju Dinkar, Nilesh Kumar and Kailash Kumar
Affiliation:
- Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
Keywords:
Diarrhoea, nausea, vomiting, loose stool, weight loss, subclinical hypothyroidism.
Abstract:
Background: Hypothyroidism is a commonly encountered endocrine disorder presenting
in various clinical settings. It usually presents with classic manifestations, which are readily
recognized and, therefore, easy to diagnose. However, occasionally, patients present with unusual
symptoms, which becomes a challenge to diagnose. Thyroid dysfunction affects many body organs,
including the gut and viscera. Studies show that intestinal motility might be affected by multiple
factors, such as neuromuscular dysfunction, myopathy, or alterations in hormone receptors.
Case Presentation: Here, we present the first case of a 21-year-old female student who had complaints
of recurrent nausea, vomiting, loose stool, abdominal pain, and weight loss. In the second
case, a 25-year-old male student presented with recurrent nausea, vomiting, loose stool, and weight
loss. Their unremarkable blood routines and gastrointestinal-specific investigations failed to ascertain
the diagnosis. Later, primary hypothyroidism was established by typical biochemical abnormalities.
Conclusion: Thyroxine replacement treatment successfully resolved the presenting symptoms and
normalized biochemical reports.