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Review Article

LncRNA和MiRNA：白藜芦醇在卵巢癌研究中的新靶点

卷 30, 期 28, 2023

发表于: 22 December, 2022

页: [3238 - 3248] 页: 11

弟呕挨: 10.2174/1389201024666221111160407

价格: $65

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摘要

卵巢癌（OC）是第3位常见的妇科癌症。 OC 的生长涉及许多过程，如迁移、血管生成、增殖、细胞凋亡、侵袭和转移。因此，更好地了解卵巢肿瘤发生中复杂的分子过程可以导致更好的疾病预防和治疗措施及其诊断。长链非编码 RNA (LncRNA) 是非编码 RNA 的一个子类，比以前认为的要多样化得多。表明这些 RNA 可能通过与蛋白质结合并影响其功能在控制复杂的细胞信号传导机制中发挥作用。尽管如此，我们对 LncRNA 参与 OC 发病机制的了解仍然有限。特别是，我们还不知道如何在药理学上纠正表观突变。白藜芦醇是一种主要来源于葡萄的天然多酚，许多研究都对其进行了评估，以发现其治疗癌症的潜力。在本文中，我们旨在回顾白藜芦醇作为潜在天然产物对 lncRNA 的作用，作为 OC 的新诊断和治疗靶点，并为进一步研究提供新见解。

关键词: 卵巢癌，lncRNA，表观遗传学，妇科癌症，白藜芦醇，血管生成。

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