Title:Correlation between Diabetes Mellitus and Peri-implantitis: A Systematic
Review
Volume: 23
Issue: 5
Author(s): Mario Dioguardi, Stefania Cantore*, Cristian Quarta, Diego Sovereto, Nicoletta Zerman, Francesco Pettini, Lorenzo Lo Muzio, Michele Di Cosola, Luigi Santacroce and Andrea Ballini*
Affiliation:
- Independent Researcher, Sorriso & Benessere - Ricerca e Clinica, Bari, Italy
- Department of Precision
Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy
Keywords:
Diabetes mellitus, PRISMA, peri-implantitis, glycometabolic decompensation, glycemic index, dental implants.
Abstract:
Background: Osseo-integrated implants provide effective treatment results for edentulous
patients. However, despite the high success and survival rates of dental implants, several factors,
such as poor oral hygiene and a history of periodontal disease, and systemic diseases, such as diabetes
mellitus, could influence the outcome of the treatment. In fact, poor glycemic control can affect the
healing process. Diabetes mellitus is considered a relative contraindication for dental implant therapy
due to the fact that the success rates of the implants seem to be lower in diabetic patients, even if
there is no total agreement among the results reported in the literature. The analysis of peri-implant
inflammation indices, bone loss around the implant and glycemic index can provide us with useful
information on the relationship between glycaemia in diabetic patients and the course of peri-implantitis,
as well as implant success in the short term.
Objective: The purpose of this review is to establish how peri-implant inflammation parameters vary
in diabetic versus non-diabetic patients.
Methods: This review was conducted on the basis of PRISMA. The search was conducted by three
independent reviewers searching for keywords in three databases: PubMed, Scopus, Web Of Sciences
(WOS), and the Cochrane Central Register of Controlled Trial.
Results: A total of 1159 records were identified, and 11 articles were included in the qualitative
analysis.
Conclusion: The analysis of the extracted data from the included studies suggests that some periimplant
inflammation indices, such as bleeding on probing and bone loss around the implant, appear
to be increased in diabetic patients with glycometabolic decompensation, compared with control not
affected by diabetes mellitus.