Title:Antimicrobial Application of Chitosan Derivatives and their Nanocomposites
Volume: 30
Issue: 15
关键词:
壳聚糖衍生物,可溶性壳聚糖衍生物,抗菌活性,结构形式,纳米材料,纳米复合材料。
摘要: Chitosan is derived from chitin polysaccharide, the main component of crustacean
shells. Chitosan is a biocompatible, nontoxic, and biodegradable polymer soluble
in acidic solutions. It is widely used in the medical and pharmaceutical fields. Antimicrobial
activities of chitosan against different bacterial, fungal, and viral pathogens have
been considered one of its attractive properties, making chitosan valuable for biological
applications, including textile, food, tissue engineering, agriculture, and environmental
protection. Additionally, chitosan has beneficial effects on livestock, poultry, fish, and
crustaceans, which can enhance immunity, improve feed conversion, and promote
growth. However, the water solubility of chitosan influences antimicrobial capabilities,
limiting its application. In the present work, we reviewed the preparation, factors affecting
antimicrobial activity, morphological structure, antimicrobial mechanism, and application
of chitosan derivatives, and the problems and prospects were pointed out. Collectively,
this review provided an update on the application of chitosan derivatives and their
potential for further advanced applications in the antimicrobial field.