Title:Artificial Intelligence in Accelerating Drug Discovery and
Development
Volume: 17
Issue: 1
Author(s): Anushree Tripathi*, Krishna Misra*, Richa Dhanuka and Jyoti Prakash Singh
Affiliation:
- Department of Computer Science and Engineering, National Institute of Technology Patna (NITP), Patna-800005, India
- Department of Applied Science, Indian Institute of Information Technology Allahabad (IIITA), Prayagraj-
211015, India
Keywords:
Drug design, bioinformatics, artificial intelligence (AI), pharmaceutical applications, COVID-19, machine learning (ML).
Abstract: Drug discovery and development are critical processes that enable the treatment
of wide variety of health-related problems. These are time-consuming, tedious, complicated,
and costly processes. Numerous difficulties arise throughout the entire process of drug
discovery, from design to testing. Corona Virus Disease 2019 (COVID-19) has recently
posed a significant threat to global public health. SARS-Cov-2 and its variants are rapidly
spreading in humans due to their high transmission rate. To effectively treat COVID-19,
potential drugs and vaccines must be developed quickly. The advancement of artificial intelligence
has shifted the focus of drug development away from traditional methods and
toward bioinformatics tools. Computer-aided drug design techniques have demonstrated
tremendous utility in dealing with massive amounts of biological data and developing efficient
algorithms. Artificial intelligence enables more effective approaches to complex
problems associated with drug discovery and development through the use of machine
learning. Artificial intelligence-based technologies improve the pharmaceutical industry's
ability to discover effective drugs. This review summarizes significant challenges encountered
during the drug discovery and development processes, as well as the applications of
artificial intelligence-based methods to overcome those obstacles in order to provide effective
solutions to health problems. This may provide additional insight into the mechanism
of action, resulting in the development of vaccines and potent substitutes for repurposed
drugs that can be used to treat not only COVID-19 but also other ailments.