Title:Feeding Pattern, Circadian Rhythm, and Immune Function: What do we know
about?
Volume: 28
Issue: 30
Author(s): Thiago Barros Estanislau, Karsten Kruger, José Cesar Rosa-Neto, Camila S. Padilha, Daniela Caetano Gonçalves, Luciele Guerra Minuzzi and Fábio Santos Lira*
Affiliation:
- Department of Physical Education, Exercise and Immunometabolism Research Group, Postgraduation
Program in Movement Sciences, Universidade Estadual Paulista (UNESP), Presidente Prudente, Brazil
- Faculty of Sports
Science and Physical Education, Research Center for Sports and Physical Activity, University of Coimbra, Coimbra, Portugal
Keywords:
Clock genes, nutrition, immunonutrition, obesity, circadian rhythm, immune function.
Abstract: Feeding pattern is related to health status or chronic diseases, and this depends on the individual’s
eating habits. Feeding organized with the right time to start and end during the day, promotes an internal biological
rhythm, favoring molecular synchronization of the clock genes, which impose an effect on metabolism
and immune cells, creating a physiological response related to a healthy profile. On the other hand, a feeding
pattern disorganized, without the right time to start and end eating during the day, might lead to nonsynchronization
of the clock genes, a disruption condition, which is related to chronic diseases, such as obesity
and diabetes type 2. A strategy that should be adopted to favor molecular synchronization is time-restricted eating
(TRE), which can organize the initial and end of the eating patterns during the day. Our review points out
some cues that suggest TRE as an efficient strategy for healthy profile and can be a good intervention for the
treatment of chronic diseases.