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Review Article

心血管疾病中的铁死亡和硫化氢

卷 30, 期 16, 2023

发表于: 26 September, 2022

页: [1848 - 1859] 页: 12

弟呕挨: 10.2174/0929867329666220630144648

价格: $65

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摘要

铁死亡是一种依赖铁的细胞死亡，其特征是脂质活性氧的积累；各种调节机制影响铁死亡的过程。心血管疾病（CVD）的迅速增加是一个极其紧迫的问题。CVD的特点是心脏和血管逐渐恶化，最终导致循环系统紊乱。然而，越来越多的证据强调了铁死亡在CVD中的关键作用。硫化氢在抗氧化应激中起着重要作用，它可能参与铁死亡的一般机制，并通过一些信号分子对其进行调节。本文综述了硫化氢对铁死亡和心血管疾病的影响，特别是抗氧化应激的影响，为CVD的临床研究提供了更有效的方向。

关键词: 硫化氢，心血管疾病，铁死亡，氧化应激，信号分子，机制。

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