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Current Traditional Medicine

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ISSN (Print): 2215-0838
ISSN (Online): 2215-0846

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Review Article

Effect of Probiotic Lactobacillus helveticus on Various Health Disorders

Author(s): Pooja Verma, Rohit Dutt and Siraj Anwar*

Volume 9, Issue 4, 2023

Published on: 01 November, 2022

Article ID: e230622206362 Pages: 9

DOI: 10.2174/2215083808666220623161236

Price: $65

Abstract

The gut microbiota has been linked to the pathogenesis of stress-related illnesses in a growing number of research. Chronic stress may alter behaviour, cognition, biochemistry, and gut flora. Gut bacteria may impact the brain and body by communicating with the host through the microbiota- gut-brain axis (mostly immunological, neuroendocrine, and neurological pathways). It is thought that taking probiotics might help with persistent stress-induced depression. Lactobacillus helveticus is a commonly used industrial thermophilic starter in manufacturing a variety of cheeses by fermenting milk. An increasing amount of scientific data suggests that strains of L. helveticus exhibit health-promoting qualities and their technical significance. In this review, we summarize the findings of several main literature publications on the capacity of L. helveticus strains to affect human health favourably.

Keywords: Anxiety, depression, early-life stress, hypotension, Lactobacillus helveticus, probiotics.

Graphical Abstract

[1]
Giraffa G. Lactobacillus helveticus: Importance in food and health. Front Microbiol 2014; 5: 338.
[http://dx.doi.org/10.3389/fmicb.2014.00338] [PMID: 25071750]
[2]
Ljungh A, Wadström T. Lactic acid bacteria as probiotics. Curr Issues Intest Microbiol 2006; 7(2): 73-89.
[PMID: 16875422]
[3]
Russo F, Linsalata M, Orlando A. Probiotics against neoplastic transformation of gastric mucosa: Effects on cell proliferation and polyamine metabolism. World J Gastroenterol 2014; 20(37): 13258-72.
[http://dx.doi.org/10.3748/wjg.v20.i37.13258] [PMID: 25309063]
[4]
Vyas U, Ranganathan N. Probiotics, prebiotics, and synbiotics: Gut and beyond. 2012; 2012
[http://dx.doi.org/10.1155/2012/872716]
[5]
Barouei J, Adams MC, Hodgson DM. Prophylactic role of maternal administration of probiotics in the prevention of irritable bowel syndrome. Med Hypotheses 2009; 73(5): 764-7.
[http://dx.doi.org/10.1016/j.mehy.2009.04.023] [PMID: 19481357]
[6]
Hörmannsperger G, Haller D. Molecular crosstalk of probiotic bacteria with the intestinal immune system: Clinical relevance in the context of inflammatory bowel disease. Int J Med Microbiol 2010; 300(1): 63-73.
[http://dx.doi.org/10.1016/j.ijmm.2009.08.006] [PMID: 19828372]
[7]
Distrutti E, O’Reilly JA, McDonald C, et al. Modulation of intestinal microbiota by the probiotic VSL resets brain gene expression and ameliorates the age-related deficit in LTP. PLoS One 2014; 9(9): e106503.
[http://dx.doi.org/10.1371/journal.pone.0106503] [PMID: 25202975]
[8]
Cleck JN, Blendy JA. Making a bad thing worse: Adverse effects of stress on drug addiction. J Clin Invest 2008; 118(2): 454-61.
[http://dx.doi.org/10.1172/JCI33946] [PMID: 18246196]
[9]
Hotel AC, Cordoba A. Health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria. Prevention 2001; 5(1): 1-0.
[10]
Davari S, Talaei SA, Alaei H, Salami M. Probiotics treatment improves diabetes-induced impairment of synaptic activity and cognitive function: Behavioral and electrophysiological proofs for microbiome-gut-brain axis. Neuroscience 2013; 240: 287-96.
[http://dx.doi.org/10.1016/j.neuroscience.2013.02.055] [PMID: 23500100]
[11]
Bravo JA, Forsythe P, Chew MV, et al. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Natl Acad Sci USA 2011; 108(38): 16050-5.
[http://dx.doi.org/10.1073/pnas.1102999108] [PMID: 21876150]
[12]
Arseneault-Bréard J, Rondeau I, Gilbert K, et al. Combination of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 reduces post-myocardial infarction depression symptoms and restores intestinal permeability in a rat model. Br J Nutr 2012; 107(12): 1793-9.
[http://dx.doi.org/10.1017/S0007114511005137] [PMID: 21933458]
[13]
Luo J, Wang T, Liang S, Hu X, Li W, Jin F. Ingestion of Lactobacillus strain reduces anxiety and improves cognitive function in the hyperammonemia rat. Sci China Life Sci 2014; 57(3): 327-35.
[http://dx.doi.org/10.1007/s11427-014-4615-4] [PMID: 24554471]
[14]
Aihara K, Kajimoto O, Hirata H, Takahashi R, Nakamura Y. Effect of powdered fermented milk with Lactobacillus helveticus on subjects with high-normal blood pressure or mild hypertension. J Am Coll Nutr 2005; 24(4): 257-65.
[http://dx.doi.org/10.1080/07315724.2005.10719473] [PMID: 16093403]
[15]
Ohsawa K, Uchida N, Ohki K, Nakamura Y, Yokogoshi H. Lactobacillus helveticus-fermented milk improves learning and memory in mice. Nutr Neurosci 2015; 18(5): 232-40.
[http://dx.doi.org/10.1179/1476830514Y.0000000122] [PMID: 24694020]
[16]
Baba H, Masuyama A, Yoshimura C, Aoyama Y, Takano T, Ohki K. Oral intake of Lactobacillus helveticus-fermented milk whey decreased transepidermal water loss and prevented the onset of sodium dodecylsulfate-induced dermatitis in mice. Biosci Biotechnol Biochem 2010; 74(1): 18-23.
[http://dx.doi.org/10.1271/bbb.90370] [PMID: 20057148]
[17]
Ikarashi N, Fukuda N, Ochiai M, et al. Lactobacillus helveticus-fermented milk whey suppresses melanin production by inhibiting tyrosinase through decreasing MITF expression. Nutrients 2020; 12(7): 2082.
[http://dx.doi.org/10.3390/nu12072082] [PMID: 32674403]
[18]
Jauhiainen T, Vapaatalo H, Poussa T, Kyrönpalo S, Rasmussen M, Korpela R. Lactobacillus helveticus fermented milk lowers blood pressure in hypertensive subjects in 24-h ambulatory blood pressure measurement. Am J Hypertens 2005; 18(12 Pt 1): 1600-5.
[http://dx.doi.org/10.1016/j.amjhyper.2005.06.006] [PMID: 16364832]
[19]
Seppo L, Jauhiainen T, Poussa T, Korpela R. A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects. Am J Clin Nutr 2003; 77(2): 326-30.
[http://dx.doi.org/10.1093/ajcn/77.2.326] [PMID: 12540390]
[20]
Beevers G, Lip GY, O’Brien E. ABC of hypertension: The pathophysiology of hypertension. BMJ 2001; 322(7291): 912-6.
[http://dx.doi.org/10.1136/bmj.322.7291.912] [PMID: 11302910]
[21]
Cremonesi P, Chessa S, Castiglioni B. Genome sequence and analysis of Lactobacillus helveticus. Front Microbiol 2013; 3: 435.
[http://dx.doi.org/10.3389/fmicb.2012.00435] [PMID: 23335916]
[22]
Taverniti V, Guglielmetti S. Health-promoting properties of Lactobacillus helveticus. Front Microbiol 2012; 3: 392.
[http://dx.doi.org/10.3389/fmicb.2012.00392] [PMID: 23181058]
[23]
Vitali B, Ndagijimana M, Cruciani F, et al. Impact of a synbiotic food on the gut microbial ecology and metabolic profiles. BMC Microbiol 2010; 10(1): 4.
[http://dx.doi.org/10.1186/1471-2180-10-4] [PMID: 20055983]
[24]
Cavallini DC, Suzuki JY, Abdalla DS, et al. Influence of a probiotic soy product on fecal microbiota and its association with cardiovascular risk factors in an animal model. Lipids Health Dis 2011; 10(1): 126.
[http://dx.doi.org/10.1186/1476-511X-10-126] [PMID: 21801422]
[25]
Kimoto-Nira H, Suzuki C, Kobayashi M, Sasaki K, Mizumachi K. Inhibition of leukotriene B4 production in murine macrophages by lactic acid bacteria. Int J Food Microbiol 2009; 129(3): 321-4.
[http://dx.doi.org/10.1016/j.ijfoodmicro.2008.12.023] [PMID: 19178973]
[26]
Vitali B, Ndagijimana M, Maccaferri S, Biagi E, Guerzoni ME, Brigidi P. An in vitro evaluation of the effect of probiotics and prebiotics on the metabolic profile of human microbiota. Anaerobe 2012; 18(4): 386-91.
[http://dx.doi.org/10.1016/j.anaerobe.2012.04.014] [PMID: 22579985]
[27]
Duncan SH, Louis P, Flint HJ. Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product. Appl Environ Microbiol 2004; 70(10): 5810-7.
[http://dx.doi.org/10.1128/AEM.70.10.5810-5817.2004] [PMID: 15466518]
[28]
Canani RB, Costanzo MD, Leone L, Pedata M, Meli R, Calignano A. Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J Gastroenterol 2011; 17(12): 1519-28.
[http://dx.doi.org/10.3748/wjg.v17.i12.1519] [PMID: 21472114]
[29]
Atassi F, Brassart D, Grob P, Graf F, Servin AL. In vitro antibacterial activity of Lactobacillus helveticus strain KS300 against diarrhoeagenic, uropathogenic and vaginosis-associated bacteria. J Appl Microbiol 2006; 101(3): 647-54.
[http://dx.doi.org/10.1111/j.1365-2672.2006.02933.x] [PMID: 16907815]
[30]
Zendeboodi F, Khorshidian N, Mortazavian AM, da Cruz AG. Probiotic: Conceptualization from a new approach. Curr Opin Food Sci 2020; 32: 103-23.
[http://dx.doi.org/10.1016/j.cofs.2020.03.009]
[31]
Maldonado Galdeano C, Cazorla SI, Lemme Dumit JM, Vélez E, Perdigón G. Beneficial effects of probiotic consumption on the immune system. Ann Nutr Metab 2019; 74(2): 115-24.
[http://dx.doi.org/10.1159/000496426] [PMID: 30673668]
[32]
Bos K, Zeanah CH, Fox NA, Drury SS, McLaughlin KA, Nelson CA. Psychiatric outcomes in young children with a history of institutionalization. Harv Rev Psychiatry 2011; 19(1): 15-24.
[http://dx.doi.org/10.3109/10673229.2011.549773] [PMID: 21250893]
[33]
Buckingham ET, Daniolos P. Longitudinal outcomes for victims of child abuse. Curr Psychiatry Rep 2013; 15(2): 342.
[http://dx.doi.org/10.1007/s11920-012-0342-3] [PMID: 23307564]
[34]
Newman DL, Moffitt TE, Caspi A, Magdol L, Silva PA, Stanton WR. Psychiatric disorder in a birth cohort of young adults: Prevalence, comorbidity, clinical significance, and new case incidence from ages 11 to 21. J Consult Clin Psychol 1996; 64(3): 552-62.
[http://dx.doi.org/10.1037/0022-006X.64.3.552] [PMID: 8698949]
[35]
Lee FS, Heimer H, Giedd JN, et al. Mental health. Adolescent mental health-opportunity and obligation. Science 2014; 346(6209): 547-9.
[http://dx.doi.org/10.1126/science.1260497] [PMID: 25359951]
[36]
Mayer EA, Knight R, Mazmanian SK, Cryan JF, Tillisch K. Gut microbes and the brain: Paradigm shift in neuroscience. J Neurosci 2014; 34(46): 15490-6.
[http://dx.doi.org/10.1523/JNEUROSCI.3299-14.2014] [PMID: 25392516]
[37]
Chitkara DK, van Tilburg MA, Blois-Martin N, Whitehead WE. Early life risk factors that contribute to irritable bowel syndrome in adults: A systematic review. Am J Gastroenterol 2008; 103(3): 765-74.
[http://dx.doi.org/10.1111/j.1572-0241.2007.01722.x] [PMID: 18177446]
[38]
Kendall-Tackett KA. Physiological correlates of childhood abuse: Chronic hyperarousal in PTSD, depression, and irritable bowel syndrome. Child Abuse Negl 2000; 24(6): 799-810.
[http://dx.doi.org/10.1016/S0145-2134(00)00136-8] [PMID: 10888019]
[39]
O’Mahony SM, Marchesi JR, Scully P, et al. Early life stress alters behavior, immunity, and microbiota in rats: Implications for irritable bowel syndrome and psychiatric illnesses. Biol Psychiatry 2009; 65(3): 263-7.
[http://dx.doi.org/10.1016/j.biopsych.2008.06.026] [PMID: 18723164]
[40]
Foster JA, McVey Neufeld KA. Gut-brain axis: How the microbiome influences anxiety and depression. Trends Neurosci 2013; 36(5): 305-12.
[http://dx.doi.org/10.1016/j.tins.2013.01.005] [PMID: 23384445]
[41]
Logan AC, Katzman M. Major depressive disorder: Probiotics may be an adjuvant therapy. Med Hypotheses 2005; 64(3): 533-8.
[http://dx.doi.org/10.1016/j.mehy.2004.08.019] [PMID: 15617861]
[42]
Sherman PM, Ossa JC, Johnson-Henry K. Unraveling mechanisms of action of probiotics. Nutr Clin Pract 2009; 24(1): 10-4.
[http://dx.doi.org/10.1177/0884533608329231] [PMID: 19244144]
[43]
Desbonnet L, Garrett L, Clarke G, Kiely B, Cryan JF, Dinan TG. Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression. Neuroscience 2010; 170(4): 1179-88.
[http://dx.doi.org/10.1016/j.neuroscience.2010.08.005] [PMID: 20696216]
[44]
Talbott SM, Talbott JA, Stephens BJ, Oddou MP. Modulation of gut-brain axis improves microbiome, metabolism, and mood. Funct Food Health Dis 2020; 10(1): 37-54.
[http://dx.doi.org/10.31989/ffhd.v10i1.685]
[45]
Messaoudi M, Violle N, Bisson JF, Desor D, Javelot H, Rougeot C. Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers. Gut Microbes 2011; 2(4): 256-61.
[http://dx.doi.org/10.4161/gmic.2.4.16108] [PMID: 21983070]
[46]
Ghavami A, Khorvash F, Heidari Z, Khalesi S, Askari G. Effect of synbiotic supplementation on migraine characteristics and inflammatory biomarkers in women with migraine: Results of a randomized controlled trial. Pharmacol Res 2021; 169: 105668.
[http://dx.doi.org/10.1016/j.phrs.2021.105668] [PMID: 33989763]
[47]
Gómez-Eguílaz M, Ramón-Trapero JL, Pérez-Martínez L, Blanco JR. The beneficial effect of probiotics as a supplementary treatment in drug-resistant epilepsy: A pilot study. Benef Microbes 2018; 9(6): 875-81.
[http://dx.doi.org/10.3920/BM2018.0018] [PMID: 30198325]
[48]
Cooksy LJ, Gill P, Kelly PA. The program logic model as an integrative framework for a multimethod evaluation. Eval Program Plann 2001; 24(2): 119-28.
[http://dx.doi.org/10.1016/S0149-7189(01)00003-9]
[49]
Kessler RC, Amminger GP, Aguilar-Gaxiola S, Alonso J, Lee S, Ustün TB. Age of onset of mental disorders: A review of recent literature. Curr Opin Psychiatry 2007; 20(4): 359-64.
[http://dx.doi.org/10.1097/YCO.0b013e32816ebc8c] [PMID: 17551351]
[50]
Merikangas KR, Nakamura EF, Kessler RC. Epidemiology of mental disorders in children and adolescents. Dialogues Clin Neurosci 2009; 11(1): 7-20.
[http://dx.doi.org/10.31887/DCNS.2009.11.1/krmerikangas] [PMID: 19432384]
[51]
Schneider M. Adolescence as a vulnerable period to alter rodent behavior. Cell Tissue Res 2013; 354(1): 99-106.
[http://dx.doi.org/10.1007/s00441-013-1581-2] [PMID: 23430475]
[52]
Paus T, Keshavan M, Giedd JN. Why do many psychiatric disorders emerge during adolescence? Nat Rev Neurosci 2008; 9(12): 947-57.
[http://dx.doi.org/10.1038/nrn2513] [PMID: 19002191]
[53]
Keller MB, Lavori PW, Wunder J, Beardslee WR, Schwartz CE, Roth J. Chronic course of anxiety disorders in children and adolescents. J Am Acad Child Adolesc Psychiatry 1992; 31(4): 595-9.
[http://dx.doi.org/10.1097/00004583-199207000-00003] [PMID: 1644719]
[54]
Schneier FR, Johnson J, Hornig CD, Liebowitz MR, Weissman MM. Social phobia. Comorbidity and morbidity in an epidemiologic sample. Arch Gen Psychiatry 1992; 49(4): 282-8.
[http://dx.doi.org/10.1001/archpsyc.1992.01820040034004] [PMID: 1558462]
[55]
Rodríguez JM, Murphy K, Stanton C, et al. The composition of the gut microbiota throughout life, with an emphasis on early life. Microb Ecol Health Dis 2015; 26(1): 26050.
[PMID: 25651996]
[56]
Delzenne NM, Neyrinck AM, Bäckhed F, Cani PD. Targeting gut microbiota in obesity: Effects of prebiotics and probiotics. Nat Rev Endocrinol 2011; 7(11): 639-46.
[http://dx.doi.org/10.1038/nrendo.2011.126] [PMID: 21826100]
[57]
Abildgaard A, Elfving B, Hokland M, Lund S, Wegener G. Probiotic treatment protects against the pro-depressant-like effect of high-fat diet in flinders sensitive line rats. Brain Behav Immun 2017; 65: 33-42.
[http://dx.doi.org/10.1016/j.bbi.2017.04.017] [PMID: 28450222]
[58]
Reis DJ, Ilardi SS, Punt SEW. The anxiolytic effect of probiotics: A systematic review and meta-analysis of the clinical and preclinical literature. PLoS One 2018; 13(6): e0199041.
[http://dx.doi.org/10.1371/journal.pone.0199041] [PMID: 29924822]
[59]
Eskandarzadeh S, Effatpanah M, Khosravi-Darani K, et al. Efficacy of a multispecies probiotic as adjunctive therapy in generalized anxiety disorder: A double blind, randomized, placebo-controlled trial. Nutr Neurosci 2021; 24(2): 102-8.
[http://dx.doi.org/10.1080/1028415X.2019.1598669] [PMID: 31516094]
[60]
Lew LC, Hor YY, Yusoff NAA, et al. Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study. Clin Nutr 2019; 38(5): 2053-64.
[http://dx.doi.org/10.1016/j.clnu.2018.09.010] [PMID: 30266270]
[61]
Zhang Z, Chen L, Zhong J, Gao P, Oudit GY. ACE2/Ang-(1-7) signaling and vascular remodeling. Sci China Life Sci 2014; 57(8): 802-8.
[http://dx.doi.org/10.1007/s11427-014-4693-3] [PMID: 25104453]
[62]
Liang S, Wang T, Hu X, et al. Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress. Neuroscience 2015; 310: 561-77.
[http://dx.doi.org/10.1016/j.neuroscience.2015.09.033] [PMID: 26408987]
[63]
Niu Y, Liang S, Wang T, et al. Pre-Gestational intake of Lactobacillus helveticus NS8 has anxiolytic effects in adolescent Sprague Dawley offspring. Brain Behav 2020; 10(9): e01714.
[http://dx.doi.org/10.1002/brb3.1714] [PMID: 32681606]
[64]
Griffiths MW, Tellez AM. Lactobacillus helveticus: The proteolytic system. Front Microbiol 2013; 4: 30.
[http://dx.doi.org/10.3389/fmicb.2013.00030] [PMID: 23467265]
[65]
Bian X, Evivie SE, Muhammad Z, et al. In vitro assessment of the antimicrobial potentials of Lactobacillus helveticus strains isolated from traditional cheese in Sinkiang China against food-borne pathogens. Food Funct 2016; 7(2): 789-97.
[http://dx.doi.org/10.1039/C5FO01041A] [PMID: 26648272]
[66]
Foster LM, Tompkins TA, Dahl WJ. A comprehensive post-market review of studies on a probiotic product containing Lactobacillus helveticus R0052 and Lactobacillus rhamnosus R0011. Benef Microbes 2011; 2(4): 319-34.
[http://dx.doi.org/10.3920/BM2011.0032] [PMID: 22146691]
[67]
Zoumpopoulou G. Production of bioactive peptides and probiotic potential of lactic acid bacteria isolated from traditional Greek dairy products. Megaron Athens International Conference Center Athens, Greece 2016; 2-26.
[68]
Hussain M, Awan FR, Gujjar A, Hafeez S, Islam M. A case control association study of ACE gene polymorphism (I/D) with hypertension in Punjabi population from Faisalabad, Pakistan. Clin Exp Hypertens 2018; 40(2): 186-91.
[http://dx.doi.org/10.1080/10641963.2017.1356842] [PMID: 29058472]
[69]
Chen X, Du X, Wang W, et al. Isolation and identification of cultivable lactic acid bacteria in traditional fermented milk of Tibet in China. Int J Dairy Technol 2010; 63(3): 437-44.
[http://dx.doi.org/10.1111/j.1471-0307.2010.00595.x]
[70]
Wang J, Li C, Xue J, et al. Fermentation characteristics and angiotensin I-converting enzyme-inhibitory activity of Lactobacillus helveticus isolate H9 in cow milk, soy milk, and mare milk. J Dairy Sci 2015; 98(6): 3655-64.
[http://dx.doi.org/10.3168/jds.2015-9336] [PMID: 25892687]
[71]
Sherwin E, Rea K, Dinan TG, Cryan JF. A gut (microbiome) feeling about the brain. Curr Opin Gastroenterol 2016; 32(2): 96-102.
[http://dx.doi.org/10.1097/MOG.0000000000000244] [PMID: 26760398]
[72]
Sen S, Duman R, Sanacora G. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: Meta-analyses and implications. Biol Psychiatry 2008; 64(6): 527-32.
[http://dx.doi.org/10.1016/j.biopsych.2008.05.005] [PMID: 18571629]
[73]
Desbonnet L, Garrett L, Clarke G, Bienenstock J, Dinan TG. The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat. J Psychiatr Res 2008; 43(2): 164-74.
[http://dx.doi.org/10.1016/j.jpsychires.2008.03.009] [PMID: 18456279]
[74]
Nishino R, Mikami K, Takahashi H, et al. Commensal microbiota modulate murine behaviors in a strictly contamination-free environment confirmed by culture-based methods. Neurogastroenterol Motil 2013; 25(6): 521-8.
[http://dx.doi.org/10.1111/nmo.12110] [PMID: 23480302]
[75]
Savignac HM, Tramullas M, Kiely B, Dinan TG, Cryan JF. Bifidobacteria modulate cognitive processes in an anxious mouse strain. Behav Brain Res 2015; 287: 59-72.
[http://dx.doi.org/10.1016/j.bbr.2015.02.044] [PMID: 25794930]
[76]
Vinderola G, Matar C, Perdigón G. Milk fermentation products of L. helveticus R389 activate calcineurin as a signal to promote gut mucosal immunity. BMC Immunol 2007; 8(1): 19.
[http://dx.doi.org/10.1186/1471-2172-8-19] [PMID: 17825099]
[77]
Capcarova M, Hascik P, Kolesarova A, Kacaniova M, Mihok M, Pal G. The effect of selected microbial strains on internal milieu of broiler chickens after peroral administration. Res Vet Sci 2011; 91(1): 132-7.
[http://dx.doi.org/10.1016/j.rvsc.2010.07.022] [PMID: 20723955]
[78]
Baba H, Masuyama A, Takano T. Short communication: Effects of Lactobacillus helveticus-fermented milk on the differentiation of cultured normal human epidermal keratinocytes. J Dairy Sci 2006; 89(6): 2072-5.
[http://dx.doi.org/10.3168/jds.S0022-0302(06)72275-5] [PMID: 16702271]
[79]
Neufeld KA, Foster JA. Effects of gut microbiota on the brain: Implications for psychiatry. J Psychiatry Neurosci 2009; 34(3): 230-1.
[PMID: 19448854]
[80]
Forsythe P, Sudo N, Dinan T, Taylor VH, Bienenstock J. Mood and gut feelings. Brain Behav Immun 2010; 24(1): 9-16.
[http://dx.doi.org/10.1016/j.bbi.2009.05.058] [PMID: 19481599]
[81]
Girard SA, Bah TM, Kaloustian S, et al. Lactobacillus helveticus and Bifidobacterium longum taken in combination reduce the apoptosis propensity in the limbic system after myocardial infarction in a rat model. Br J Nutr 2009; 102(10): 1420-5.
[http://dx.doi.org/10.1017/S0007114509990766] [PMID: 19563693]
[82]
Wann BP, Boucher M, Kaloustian S, Nim S, Godbout R, Rousseau G. Apoptosis detected in the amygdala following myocardial infarction in the rat. Biol Psychiatry 2006; 59(5): 430-3.
[http://dx.doi.org/10.1016/j.biopsych.2005.07.018] [PMID: 16202395]
[83]
Yamamura S, Morishima H, Kumano-go T, et al. The effect of Lactobacillus helveticus fermented milk on sleep and health perception in elderly subjects. Eur J Clin Nutr 2009; 63(1): 100-5.
[http://dx.doi.org/10.1038/sj.ejcn.1602898] [PMID: 17851460]
[84]
Callanan M, Kaleta P, O’Callaghan J, et al. Genome sequence of Lactobacillus helveticus, an organism distinguished by selective gene loss and insertion sequence element expansion. J Bacteriol 2008; 190(2): 727-35.
[http://dx.doi.org/10.1128/JB.01295-07] [PMID: 17993529]
[85]
Pecoraro N, Reyes F, Gomez F, Bhargava A, Dallman MF. Chronic stress promotes palatable feeding, which reduces signs of stress: Feedforward and feedback effects of chronic stress. Endocrinology 2004; 145(8): 3754-62.
[http://dx.doi.org/10.1210/en.2004-0305] [PMID: 15142987]
[86]
Ait-Belgnaoui A, Payard I, Rolland C, et al. Bifidobacterium longum and Lactobacillus helveticus synergistically suppress stress-related visceral hypersensitivity through hypothalamic-pituitary-adrenal axis modulation. J Neurogastroenterol Motil 2018; 24(1): 138-46.
[http://dx.doi.org/10.5056/jnm16167] [PMID: 29291614]

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