Title:Phytochemical Characterization and Screening of the Anti-Pneumonia
(Anti-COVID-19, Anti-Fungal, and Anti-Bacterial) Activities of Cuscuta
Campestris Extract
Volume: 20
Issue: 8
Author(s): Haidar Saify Nabiabad*, Massoume Amini and Serwet Demirdas
Affiliation:
- Department of Biotechnology, Bu-Ali Sina University, Hamadan, Iran
Keywords:
Antibacterial, Anti-COVID-19, antifungal, Cuscutacampestris, GC/MS and far-red light.
Abstract:
Introduction: Although, several vaccines are being approved, no effective antiviral drug has
been developed for COVID-19 infectious. The present investigation was aimed to increase the essential
oils of Cuscuta campestris using far-red light treatment and examine the potential of crude extracts of C.
campestris against selected pneumonia pathogens and COVID-19.
Methods: Anti-COVID-19 activity was determined in human lung cell lines and COVID-19 positive patients.
Results: Results demonstrated that the aqueous extract had the highest amount of anti-COVID-19, antibiotic
and antioxidant activity. The far-red light treatment increased Scoparone, cineole, Benzofuran, 2, 3-
dihydro, Cinnamic acid, and Benzo[h]quinoline, 2, 4-dimethyl, which are mainly effective components
against COVID-19 inflammation and pneumonia microbes. CT scan and clinical laboratory tests in a
clinical case study, a 30-year-old woman who presented with severe 2019-nCoV, demonstrated that inhalation
of 30 mg extract nebulized/day for seven days resulted in significant improvement in consolidation
and ground-glass opacity in lungs on the seventh day of treatment.
Conclusion: It is hoped that this study leads to the introduction of some compounds that could be used to
formulate new and more potent anti-COVID-19 antibiotics, or other drugs of natural origin in medicine.
