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Letters in Organic Chemistry

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ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

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Chiral Allenylcarbonyls – Underexploited Building Blocks for Complex Synthesis

Author(s): Krishna Yadavalli* and Salvatore D. Lepore*

Volume 19, Issue 8, 2022

Published on: 01 February, 2022

Page: [597 - 601] Pages: 5

DOI: 10.2174/1570178619666211231113033

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Abstract

Chiral allenylcarbonyls such as allenoates remain underutilized in complex synthesis despite recent advances in synthesis methods to prepare them non-racemically. The field is now ripe for the employment of this class of allenes as building blocks to facilitate the construction of complex small-molecule compounds, such as bridged bicycles.

Keywords: Chiral allenylcarbonyls, complex synthesis, cyclobutene, cycloaddition, zinc, diels-alder reaction.

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