Title:From Bench Side to Bed-Travelling on a Road to Get a Safe and
Effective Vaccine against COVID-19, Day to Save the Life
Volume: 16
Issue: 1
Author(s): Suman Kumar Ray and Sukhes Mukherjee*
Affiliation:
- Department of Biochemistry, All India Institute of Medical Sciences,
Bhopal, Madhya Pradesh-462020, India
Keywords:
COVID-19, SARS-CoV-2, pandemic, immune response, vaccine, patent.
Abstract: Coronavirus Disease 2019 (COVID-19) is caused by a new strain of
coronavirus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-
2). It is the most challenging pandemic of this century. The growing
COVID-19 pandemic has triggered extraordinary efforts to restrict the virus in
numerous ways, owing to the emergence of SARS-CoV-2. Immunotherapy,
which includes artificially stimulating the immune system to generate an immunological
response, is regarded as an effective strategy for preventing and
treating several infectious illnesses and malignancies. Given the pandemic's high
fatality rate and quick expansion, an effective vaccination is urgently needed to
keep it under control. The basic goal of all COVID-19 vaccine programs is to develop
a vaccine that causes the generation of surface protein neutralizing antibodies
in subjects. The epitope discovery for the SARS-CoV-2 vaccine candidates
is likewise made using an immuno-informatics methodology. It can be
used to find the epitopes in viral proteins important for cytotoxic T cells and B
cells. A safe and effective COVID-19 vaccine that can elicit the necessary immune
response is necessary to end the epidemic. The global search for a safe and
effective COVID-19 vaccine is yielding results. More than a dozen vaccines
have already been approved around the world, with many more in the clinical
trials. Patents can cover the underlying technology used to generate a vaccine,
whereas trade secrets can cover manufacturing methods and procedures.
