Title:Natural Derived Nasal Spray; A Proposed Approach for COVID-19 Disease
Control
Volume: 21
Issue: 8
Author(s): Zahra Hoseini-Tavassol, Hanieh-Sadat Ejtahed, Ahmad-Reza Soroush, Zahra Sajjadpour, Shirin Hasani-Ranjbar*Bagher Larijani
Affiliation:
- Obesity and Eating Habits Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran,Iran
Keywords:
Acute respiratory infections, COVID-19, SARS-CoV-2, natural derived ingredients, nasal sprays, carrageenan
Abstract: Considering the importance of COVID-19 disease pandemic, emerged by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in line with other studies to find appropriate
prevention or treatment methods for this virus infection, our study objective was proposing
the use of natural derived ingredients as an approach for COVID-19 disease control. Here we reviewed
previous studies on natural derived nasal sprays andfound that some known natural derived
ingredients have antiviral properties, so their topical use as a nasalspray is effective in reducing the
symptoms of respiratory infections. Moreover, such nasal sprays also have thepotential of decreasing
viral load, including titer of coronaviruses, in the nasal cavity. It seems that the use ofcarrageenan
or other herbal ingredients in the nasal spray may block the SARS-CoV-2 virus from entering
thelung cells of an affected person and can also prevent virus transmission to other susceptible persons.
Further,noticing what we know about the novel 2019 coronavirus so far, we suggested carrageenan
that has an unspecific physical antiviral activity and some other natural derived ingredients,
as a choice in coping with SARS-CoV-2 virus infection.