Title:A Comprehensive Review on Recently Detected Herbal Phytoactives
Having Anti-Diabetic Potential for Various Diabetes-Related Complications
Volume: 7
Issue: 5
Author(s): Pranay Wal*, Ankita Wal, Rashmi Saxena Pal and Priya Singh
Affiliation:
- Institute of Pharmacy , PSIT, Kanpur, 209305,India
Keywords:
Diabetes, insulin, herbal, phytoactives, potential, natural compounds.
Abstract:
Background: Diabetes is a metabolic, endocrine disorder that is featured by hyperglycemia
and glucose intolerance, primarily due to beta cell destruction, with insulin resistance playing
a secondary role. It is treated with the help of many chemical-based drugs as well as natural
derivatives.
Objective: There is an urgent need to develop new efficacious, cheaper and more available drugs to
face this growing public health challenge. Many anti-diabetic drugs are often associated with many
adverse effects.
Materials & Methods: Literature was reviewed in a narrative manner in order to obtain information
regarding active phytoactives present in different plants. Anti-diabetic drugs are often loaded
with side effects; therefore, this review was carried out for the selection of effective natural therapeutic
moieties with less or no adverse effects.
Results: In this review article, we have described the details of recently detected bioactive compounds
present in different natural substances which can be used effectively for diabetes-related adversities.
Conclusion: Natural products-based bioactive molecules have been proven to improve insulin resistance
and other related complications through suppression of inflammatory signaling pathways.
