Title:Therapeutic Potential of Equol: A Comprehensive Review
Volume: 26
Issue: 45
Author(s): Atiya Fatima*, Mohd Shariq Khan and Md. Wasi Ahmad*
Affiliation:
- Department of Chemical Engineering, Dhofar University, Salalah,Oman
- Department of Chemical Engineering, Dhofar University, Salalah,Oman
Keywords:
Bioactive molecule, equol, S-equol, isoflavone, nutraceutical, phytoestrogen, selective estrogen receptor modulator (SERM).
Abstract: Equol (4',7-isoflavandiol), is a phytoestrogenic compound, which is synthesized from parent molecule
diadzein by intestinal bacterial flora. It is among one of the most extensively researched molecule due to its
high affinity towards estrogen receptors. Its enantiomeric form S-equol has been explored in the treatment of
estrogen/androgen mediated diseases. Various therapeutic applications such as anti-cancer, cardioprotective,
antidiabetic, antiosteoporosis, anti-ageing, and neuroprotective efficacy are attributed to it. This review explored
major studies related to biochemistry and pharmacological applications of equol for human health.
