Title:Multifocal Osteolytic Lesions in Skull Bone with Mycobacterium Tuberculosis: A Case Report
Volume: 21
Issue: 5
Author(s): Milad Mellat-Ardakani, Fereshteh Ghiasvand, Malihe Hassan Nezhad, Faeze Salahshour and SeyedAhmad SeyedAlinaghi*
Affiliation:
- Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran,Iran
Keywords:
Tuberculosis, skull bone, maxillary, osteolytic lesions, destruction, Ziel Nelson staining.
Abstract: Background: Bone Tuberculosis of the skull base as well as maxillofacial and oral cavity
involvement can rarely and only occur in about 3% of the cases with systemic diseases or in case
of pulmonary involvement.
Case Presentation: A 37-year-old patient with fever and swelling in his face and neck referred to
our center. After MRI and CT scan, it was revealed that multiple erosions and destructions are seen
in the Hard Palate bones, as well as the pre-maxillary process, alveolar ridge, and the floor of maxillary
sinus on both sides. In the Ziel Nelson staining, there were 5 Acid-fast bacilli in each field.
The patient received standard anti-tuberculosis and clarithromycin therapy. In the follow-up three
months later, the patient’s condition improved and MRI showed significant remission.
Conclusion: The present case confirms that tuberculosis may occur in patients with skull bone involvement
and osteolytic lesions whose early diagnosis and treatment can result in gaining good
outcomes.
