Title:Biological and Pharmacological Effects of Gamma-oryzanol: An Updated Review of the Molecular Mechanisms
Volume: 27
Issue: 19
Author(s): Elham Ramazani, Maryam Akaberi, Seyed Ahmad Emami and Zahra Tayarani-Najaran*
Affiliation:
- Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad,Iran
Keywords:
γ-oryzanol, rice bran oil, anti-oxidant, cholesterol-lowering, anti-diabetic, pharmacological.
Abstract:
Background: Gamma-oryzanol (γ-oryzanol) is one of the rice bran oil (RBO) compounds, known as
a principal food source throughout the world. In recent numerous experimental studies, γ-oryzanol has been revealed
to have several useful pharmacological properties, such as anti-oxidant, anti-inflammatory, anti-cancer,
anti-diabetic, ameliorating unpleasant menopausal symptoms, cholesterol-lowering, improving plasma lipid pattern,
etc.
Methods: In this study, we reviewed the scientific literature published up until 2020, which has evaluated the
biological and pharmacological activity of gamma-oryzanol. This review summarizes the published data found
in PubMed, Science Direct, and Scopus.
Results and Conclusion: The present review attempts to summarize the most related articles about the pharmacological
and therapeutic potential from recent studies on γ-oryzanol to gain insights into design further studies
to achieve new evidence that confirm the observed effects.