Title:Novel Coronavirus SARS-CoV-2 (COVID-19) and Pregnancy: A Hypothetical View
Volume: 21
Issue: 8
Author(s): RG Ahmed*
Affiliation:
- Division of Anatomy and Embryology, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef,Egypt
Keywords:
SARS-CoV-2, COVID-19, Pregnancy, Offspring, Treatment, Prevention.
Abstract: The complications of the SARS-CoV-2 infection and its COVID-19 disease on mothers
and their offspring are less known. This review aimed to determine the transmission, severity, and
complications of SARS- CoV-2 infection during pregnancy. This review showed the influence of
COVID-19 disease on neonatal neurogenesis. Owing medicines that were reported for the treatment
of COVID-19 disease, this review suggested some control strategies like treatments (medicinal
plants, antiviral therapy, cellular therapy, and immunotherapy), nutrition uptake, prevention,
and recommendations. This overview showed that severe infection of SARS-CoV-2 during the early
stage of pregnancy might increase the risk of stress, panic, and anxiety. This disorder can disturb
the maternal immune system, and thus causing a neurodevelopmental disturbance. This hypothesis
may be depending on the severity and intensity of the SARS-CoV-2 infection during pregnancy.
However, vertical transmission of SARS-CoV-2 from dams to their fetuses is absent until now.
During this global pandemic disease, maintaining safety during pregnancy, vaginal delivery, and
breastfeeding may play a vital role in a healthy life for the offspring. Thus, international, and national
organizations should be continuing for perinatal management, particularly during the next pandemic
or disaster time.