Title:Overview of Coumarins and its Derivatives: Synthesis and Biological Activity
Volume: 18
Issue: 11
Author(s): Tanvi Sahni, Sunita Sharma*, Diksha Verma and Pardeep Kaur
Affiliation:
- Department of Plant Breeding and Genetics, Punjab Agricultural University, Ludhiana,India
Keywords:
Coumarin, Synthesis, derivatives, Biological activities, heterocyclic compounds, benzo-β-pyrone.
Abstract: Coumarin is a heterocyclic scaffold and its derivatives, namely Schiff bases, esters, and
hydrazides, etc., play an important role in the field of agrochemical and pharmaceutical industry
due to its structure. Over the years, various biological activities like antifungal, antimicrobial, antiviral,
anti-cancerous, anti-tumor, anti-inflammatory, anti-filarial, enzyme inhibitors, antiaflatoxigenic,
analgesics, antioxidant and Oestrogenic, etc., have been analyzed. This review covers
the latest literature and knowledge on the synthetic procedures for various coumarin and its
derivatives, their biological and pharmacological applications.