Title:Solvent-free, Silica Catalyzed Intriguing Conversion of 3- Hydrazonobutan-2-one Oxime into Biacetyl Bis-hydrazone Schiff Bases
Volume: 18
Issue: 7
Author(s): Ranjana Aggarwal*, Mona Hooda, Prince Kumar and Garima Sumran
Affiliation:
- Department of Chemistry, Kurukshetra University, Kurukshetra 136119, Haryana,India
Keywords:
3-Hydrazonobutan-2-one oxime, biacetyl bis-hydrazone Schiff bases, 3-(aryl)methylenehydrazonobutan-2-one oxime,
azine, solvent-free synthesis, silica gel.
Abstract: An expeditious and operationally simple reaction between 3-hydrazonobutan-2-one oxime
and different substituted benzaldehydes in the presence of silica afforded an unexpected product, biacetyl
bis-hydrazone Schiff bases in good yield on grinding in a mortar at room temperature, instead of
expected product 3-(aryl)methylenehydrazonobutan-2-one oxime. Mild reaction conditions involving
recyclable mineral support silica, environmentally benign and good yield in short reaction time are
remarkable advantages of this protocol. Products were characterized by IR, NMR (1H and 13C) and
elemental analyses.