Title:Discovery of Channa Striata Extracts as Regenerative Medicine in Promoting Wound Healing and Scarless Skin Regeneration
Volume: 11
Issue: 4
Author(s): Soon Hong Kwan and Mohd Nazri Ismail*
Affiliation:
- Analytical Biochemistry Research Centre (ABrC), Universiti Sains Malaysia, USM, 11800, Penang,Malaysia
Keywords:
Channa striata, fish, medicine, natural product, skin regeneration, scarless, wound healing.
Abstract: Channa striata (also known as Channa striatus) is an air-breathing freshwater snakehead
fish that is well known in the Asian region for its medicinal properties, particularly in wound
healing. It is recognised as a traditional medicine (TM), which can be served as alternative treatment
method. With the advancement of technology, researchers have made a lot of progress in
characterising the biomolecules of this fish. Various types of bioactive molecules have been
identified in the fish, and their therapeutic effects are being studied. The C. striata have exhibited
antibacterial, antinociceptive and effective wound recovery property through various pharmacology
assays. It has been regarded as a source of traditional medicine that could complement modern
medicine in promoting human health. The applications of C. striata extracts by practitioners in
treating different illnesses are discussed. Besides, the approaches towards scarless wound in future
applications involving the snakehead fish are also highlighted. Challenges and solutions to develop
an aquatic-derived drug were also covered. The Channa striata extract as a natural product has
shown great prospects for wound healing enhancement. Many biomolecules associated with
antibacterial and antinociceptive properties, which are crucial for healthy wound recovery were
identified in the species. Significant advances and researches in the region have successfully led to a
better understanding of the species, which provide a promising future for drug development.
