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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Research Article

Efficacy of Methylphenidate for Internet Gaming Disorder and Internet Addiction in Patients with Attention-Deficit/Hyperactivity Disorder

Author(s): Andrea Salvati, Gianluca Sesso*, Francesca Lenzi, Gabriele Masi and Stefano Berloffa

Volume 30, Issue 6, 2024

Published on: 31 January, 2024

Page: [477 - 483] Pages: 7

DOI: 10.2174/0113816128281014240124074845

Price: $65

Abstract

Background: Internet Gaming Disorder (IGD) and Internet Addiction (IA) are related clinical conditions often comorbid with Attention-Deficit/Hyperactivity Disorder (ADHD).

Objective: We evaluated the efficacy of MPH for IGD/IA symptoms in ADHD patients.

Methods: We enrolled 38 drug-naive patients diagnosed with ADHD (Attention-Deficit/Hyperactivity Disorder) and IGD/IA. At baseline, all patients underwent a clinical assessment for IGD/IA symptoms and then received the most appropriate therapy according to their clinical profile. Twenty-one patients received MPH (methylphenidate) treatment, and 17 patients did not. Patients were re-evaluated after three months of treatment.

Results: Findings revealed significant reductions in IGD/IA symptoms over time, while no significant effect of MPH on symptom reduction was found. Clinical predictors of symptom reduction were identified, including IQ (Intelligence Quotient) and comorbid anxiety.

Conclusion: This longitudinal prospective study contributes to the understanding of IGD/IA treatment in ADHD patients and highlights the importance of considering individual clinical characteristics when predicting treatment response. However, MPH may not directly impact IGD/IA symptom reduction.

Keywords: Internet gaming disorder, internet addiction, attention-deficit/hyperactivity disorder, methylphenidate, pharmacological interventions, intelligence quotient.

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