Abstract
A series of 7-carbamate derivatives of quercetin were synthesized. Using dichlorodiphenylmethane and benzyl bromide to partly protect the hydroxyl groups, the protected quercetin then reacted with amino acid ester isocyanates, deprotection the hydroxyls with hydrogen using a palladium on carbon catalyst, then treating with ammonia gas to give the ammonium salts of 7-carbamate derivatives of quercetin.
Keywords: Quercetin, 7-carbamate derivatives of quercetin, dichlorodiphenylmethane, isocyanate, ammonium salt
Letters in Organic Chemistry
Title: Syntheses of the Ammonium Salts of 7-Carbamate Derivatives of Quercetin
Volume: 4 Issue: 5
Author(s): Chenglong Wu, Li Cheng, Ying Li, Dong Guo, Shuyan Yu, Xianxue Wu and Yuquan Wei
Affiliation:
Keywords: Quercetin, 7-carbamate derivatives of quercetin, dichlorodiphenylmethane, isocyanate, ammonium salt
Abstract: A series of 7-carbamate derivatives of quercetin were synthesized. Using dichlorodiphenylmethane and benzyl bromide to partly protect the hydroxyl groups, the protected quercetin then reacted with amino acid ester isocyanates, deprotection the hydroxyls with hydrogen using a palladium on carbon catalyst, then treating with ammonia gas to give the ammonium salts of 7-carbamate derivatives of quercetin.
Export Options
About this article
Cite this article as:
Chenglong Wu , Li Cheng , Ying Li , Dong Guo , Shuyan Yu , Xianxue Wu and Yuquan Wei , Syntheses of the Ammonium Salts of 7-Carbamate Derivatives of Quercetin, Letters in Organic Chemistry 2007; 4 (5) . https://dx.doi.org/10.2174/157017807781212021
DOI https://dx.doi.org/10.2174/157017807781212021 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
![Wayfinder Image](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Therapeutic Potential of HDAC Inhibitors in the Treatment of Cardiac
Diseases: A Short Review
Current Drug Targets Cytokines as Anti-Angiogenic Agents in Haematological Malignancies
Current Cancer Drug Targets New Use for Old Drugs? Prospective Targets of Chloroquines in Cancer Therapy
Current Drug Targets Melatonin a Promising Candidate for DNA Double-Stranded Breaks Reduction in Patients Undergoing Abdomen-Pelvis Computed Tomography Examinations
Anti-Cancer Agents in Medicinal Chemistry circEPSTI1 Acts as a ceRNA to Regulate the Progression of Osteosarcoma
Current Cancer Drug Targets Development of Novel, Highly Cytotoxic Fusion Constructs Containing Granzyme B: Unique Mechanisms and Functions
Current Pharmaceutical Design Novel Aspects of Insulin-like Growth Factor 1/insulin Network in Chronic Inflammatory Airway Disease
Current Medicinal Chemistry Role of Mitochondrial Mechanism in Chemotherapy-Induced Peripheral Neuropathy
Current Drug Metabolism Commercial Aspects of Pharmaceutical Protein Production in Plants
Current Pharmaceutical Design Editorial (Thematic Issue: Targeted Therapies in Upper Gastrointestinal Malignancies)
Current Medicinal Chemistry Hematopoietic Stem Cell Transplantation for the Treatment of Autoimmunity in Type 1 Diabetes
Current Stem Cell Research & Therapy Radiochemical Evaluation and <i>In Vitro</i> Assessment of the Targeting Ability of a Novel <sup>99m</sup>Tc-HYNIC-RGD for U87MG Human Brain Cancer Cells
Current Radiopharmaceuticals (Iso)Flav(an)ones, Chalcones, Catechins, and Theaflavins as Anticarcinogens: Mechanisms, Anti-Multidrug Resistance and QSAR Studies
Current Medicinal Chemistry Omalizumab for Asthma: Indications, Off-Label Uses and Future Directions
Recent Patents on Inflammation & Allergy Drug Discovery Modulators of Protein-Protein Interactions – Novel Approaches in Targeting Protein Kinases and Other Pharmaceutically Relevant Biomolecules
Current Topics in Medicinal Chemistry Targeting DNA Minor Groove by Hybrid Molecules as Anticancer Agents
Current Medicinal Chemistry Transcriptional Analysis of JAK/STAT Signaling in Glioblastoma Multiforme
Current Pharmacogenomics and Personalized Medicine Cell Cycle Kinases in Osteosarcoma: Potential for Therapeutic Intervention
Current Pharmaceutical Design Viral Vectors in Cancer Immunotherapy: Which Vector for Which Strategy?
Current Gene Therapy PET and PET/CT: Conceptions, Misconceptions, and a Potential New Paradigm for Enhanced Metabolic Imaging
Current Medical Imaging