This review highlights the development of new receptors based on
enantiopure trans-cyclohexane-1,2-diamine, a chiral building block presenting unique
structural and conformational properties. Different architectures sharing this structural
motif, which were prepared following several synthetic approaches, have been
summarized from the recent literature.
Keywords: Trans-cyclohexane-1, 2-diamine, chiral receptor, nitrogen, molecular
recognition, macrocycles.