Medicinal plants have been known for their therapeutic properties for
centuries, as they are rich in uncountable and valuable phytochemical compounds.
Synthesis as well as different biological aspects of such compounds in plants increases
many folds in association with endophytes. These microbial endophytes reside in host
plants without causing any symptoms of infection so they are gaining the attention of
researchers for research in many fields such as in agriculture, medicines, environmental
studies, etc. In the recent development of research, the medicinally important family
Zygophyllaceae has a limited extent of microbial endophytes’ specificity. Very limited
studies have been conducted on bioactive compounds isolated from endophytes and
their role in health-related benefits. Therefore, this article presents a review of the
evaluation of endophytes studied in plants of Zygophyllaceae for the study of bioactive
compounds along with various biological activities. This review article will
prominently contribute to the exploration of endophytes from medicinal plants of
Zygophyllaceae as a source of bioactive and chemically novel compounds.
Keywords: Agriculture, Bioactive compounds, Environmental studies, Microbial endophytes, Zygophyllaceae.