Photodynamic therapy (PDT) is one of the most innovative therapies
currently available with no side effects. Initially introduced for the treatment of
dermatological pathologies, it is now used in numerous medical fields, as well as in
oral pathology. PDT has antimicrobial effects and can be used in several infections.
The mechanism of action of PDT is based on the application of a dye called
photosensitizer, which is activated by a precise wavelength. The photosensitizer is
activated by specific wavelengths based on the chemical characteristics. Its activation
involves the formation of reactive oxygen species that determine the death of the
altered cells. Phototherapy is a therapeutic medical treatment based on the use of a
special optical unit capable of emitting light, which can be used with or without UV
radiation. Phototherapy acts as a natural and non-invasive therapy, capable of
transferring energy to the cells of the organism, promoting regenerative capabilities.
The aim of our work is to report our clinical experience in the treatment of some lip
pathological conditions with phototherapy and PDT.
Keywords: Herpes simplex 1, Lichen planus, Photodynamic therapy, Photosensitizers.