Women’s Health: A Comprehensive Guide to Common Health Issues in Women

Bone Health and Menopause: Understanding and Remodeling

Author(s): Apoorva Mishra, Soni Kumari, Saumya Das*, Manas Kumar Das, Smriti Ojha and Rohit Kumar Verma

Pp: 267-297 (31)

DOI: 10.2174/9789815256291124010015

* (Excluding Mailing and Handling)

Abstract

Menopause is a physiological condition that is caused by mainly ovarian disorders brought on by apoptosis. With age, ovarian function decreases. During menopause, women experience a wide range of symptoms and health problems, including cognition decline, heart disease, urogenital diseases, and bone fracture risk, all of which are connected to the body's declining estrogen levels. Menopause is the biggest risk factor in women over 49 to 50 years of age who have osteoporosis. The lack of estrogen encountered during the stages of perimenopause and menopause has been linked to osteoporosis. Early menopause (before age 45), along with any protracted period of low hormone levels and irregular or absent menstrual cycles, results in bone mass loss. Osteoporosis is a degenerative disorder sometimes recognized as a “silent disease” that raises the possibility of fractures caused by fragility and is characterized by a loss of bone mass and an erosion of bone structure. According to the statement, osteoporosis is both gravely underdiagnosed and undertreated. In postmenopausal women, managing their bone health entails identifying and lowering fracture risk factors through nonpharmacologic initiatives, taking medications that increase bone density and strength, minimizing risk factors through changes in lifestyle and diet, as well as using pharmacologic therapy. 


Keywords: Bone health, Estrogen, Menopause, Osteoporosis, Osteoclast

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