Nanoelectronic Devices and Applications

Recent Trends in FET and HEMT-Based Biosensors for Medical Diagnosis

Author(s): E. Raghuveera*, G. Purnachandra Rao and Trupti Ranjan Lenka

Pp: 258-270 (13)

DOI: 10.2174/9789815238242124010016

* (Excluding Mailing and Handling)

Abstract

Nowadays, a wide range of viruses, bacteria, cancers, and other diseases have emerged due to drastic changes in the environment and climate, as well as changes in human habitation and lifestyle. Some viruses, like the coronavirus (COVID19), are potentially fatal, causing a global pandemic and leading to millions of deaths worldwide. Therefore, the development of biosensors is necessary to identify these viruses and cancers at an early stage. The book chapter aims to discuss the development of biosensors based on different device technologies (FET, AlGaAs/GaAs, AlGaN/GaN) with their performance characteristics toward biosensing applications. This chapter also focuses on two important detection techniques, labelbased and label-free biosensing, and compares them with several performance factors. The performance characteristics of FET-based biosensors, AlGaAs-based biosensors, and AlGaN-based biosensors are covered in this book chapter.


Keywords: Biosensors, HEMT, Label-based detection, Label-free detection, Sensitivity, Response time.

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