Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists

Triazoles and their Derivatives as Anti-Inflammatory Agents

Author(s): Anirudh Singh Bhathiwal, Anjaneyulu Bendi* and Aditi Tiwari

Pp: 26-46 (21)

DOI: 10.2174/9789815223460124010005

* (Excluding Mailing and Handling)

Abstract

Heterocyclic compounds are a large group of organic chemical compounds that have at least one and sometimes more than one heteroatom. For their anti-fungal, anti-inflammatory, anti-bacterial, anti-cancer, and other properties, heterocyclic compounds are used a lot in pharmaceuticals, agrochemicals, veterinary products, sanitizers, antioxidants, co-polymers, and other products. Triazoles are a type of chemical compound that has a five-membered heterocyclic ring with three nitrogen atoms and are used in a significant number of different pharmaceutical applications along with anti-inflammatory agents. Nowadays, a significant amount of research is being done on triazoles as potential anti-inflammatory agents. This chapter is mainly focused on the synthesis of triazoles and their various derivatives, along with their antiinflammatory properties.


Keywords: Anti-inflammatory agents, Biological activity, Click chemistry, Drug discovery, Heterocyclic compounds, Inflammation, Medicinal chemistry, Pharmaceuticals, Triazoles.

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