Green Plant Extract-Based Synthesis of Multifunctional Nanoparticles and their Biological Activities

Protein–Nanoparticles Interactions

Author(s): Seyed Morteza Naghib* and Hamid Reza Garshasbi *

Pp: 94-139 (46)

DOI: 10.2174/9789815179156123010005

* (Excluding Mailing and Handling)


Large surface area, small size, strong optical properties, controllable structural features, variety of bioconjugation chemistries, and biocompatibility make many different types of nanoparticles (NPs), such as gold NPs, useful for many biological applications, such as biosensing, cellular imaging, disease diagnostics, drug delivery, and therapeutics. Recently, interactions between proteins and NPs have been extensively studied to understand, control, and utilize the interactions involved in biomedical applications of NPs and several biological processes, such as protein aggregation, for many diseases, including Alzheimer's. These studies also offer fundamental knowledge on changes in protein structure, protein aggregation mechanisms, and ways to unravel the roles and fates of NPs within the human body.

Keywords: Nanoparticles interactions, Protein interactions, Protein structure.

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