Methods in Drug Repurposing: Emphasis on COVID-19

Coronavirus disease 19 (COVID-19) is a pandemic situation caused by the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), and dedicated medical research finding to cure the disease are rapidly evolving globally. SARS-Co- -2 is a highly mutating virus having various strains, till the reporting of this study, COVID-19 has 5 variants, i.e., Alfa, beta, gamma, delta, and omicron. A potential way for drug development is drug repurposing has got a lot of attention. Drug repurposing is the easiest and safest way to find out the drugs to cure COVID-19. Various new drugs have been discovered and are under clinical trial for the treatment of disease. Combinatorial treatments of COVID-19 patients give a very positive response in the treatment of SARS-CoV-2. The various vaccine already has been developed to produce antibodies against COVID-19. However, a large number of research studies have been done on COVID-19. This study is dedicated to research on COVID-19 therapy by the repurposing of existing drugs and methods used for the drug repurposing.

Keywords: Combinatorial, COVID-19, Drug Repurposing, Medical Research, SARS-CoV-2, Targeted Based Approaches.